2,2,2,3′-Tetrafluoroacetophenone
2,2',3'-Tetrafluoroacetophenone (CAS: 708-64-5) is a fluorinated ketone with the molecular formula C8H4F4O. This compound serves as a valuable building block in organic synthesis, particularly for introducing trifluoromethyl and tetrafluorophenyl moieties into more complex molecules. Its primary applications lie in the development of novel pharmaceuticals, agrochemicals, and advanced materials, leveraging the unique electronic and lipophilic properties conferred by fluorine substitution.
- IUPAC
- α,α,α,3-Tetrafluoroacetophenone
- Synonyms
- 3′-TetrafluoroacetophenoneFC6H4COCF3α,α,α,3-Tetrafluoroacetophenone
Pharmaceutical Synthesis
Used as an intermediate in the synthesis of active pharmaceutical ingredients (APIs), contributing fluorine atoms that can enhance metabolic stability and binding affinity.
Agrochemical Development
Serves as a building block for creating new pesticides and herbicides, where fluorination can improve efficacy and environmental persistence profiles.
Materials Science
Incorporated into the synthesis of advanced polymers and specialty chemicals, utilizing its unique electronic properties derived from fluorine.
Research and Development
A versatile reagent for academic and industrial research laboratories exploring novel fluorinated compounds and reaction pathways.
| Molecular weight | 192.11 |
|---|---|
| Linear formula | FC6H4COCF3 |
| Assay | 99% |
| Boiling point | 79 °C/50 mmHg(lit.) |
| Density | 1.372 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.444(lit.) |
Hazard statements
- H225Highly flammable liquid and vapour
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 17 °C / 62.6 °F |
| Transport (UN / ADR) | UN 1224BE 3 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xi |
| Risk statements (R) | 11-36/37/38 |
| Safety statements (S) | 16-26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,2',3'-Tetrafluoroacetophenone used for?
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2,2',3'-Tetrafluoroacetophenone is primarily used as a building block in organic synthesis for the development of pharmaceuticals, agrochemicals, and advanced materials.
What is the CAS number and molecular formula for 2,2',3'-Tetrafluoroacetophenone?
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The CAS number is 708-64-5 and the molecular formula is C8H4F4O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2,2',3'-Tetrafluoroacetophenone with a minimum assay of 99%. This product is intended for research and chemical synthesis purposes and is not represented as USP, BP, EP, or any other pharmacopoeia grade.
How should 2,2',3'-Tetrafluoroacetophenone be handled safely?
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This compound is a flammable liquid and vapour, and causes skin, eye, and respiratory irritation. Handle with appropriate personal protective equipment, including safety goggles, face shields, gloves, and a suitable respirator, in a well-ventilated area. Refer to the Safety Data Sheet for comprehensive handling information.
Is 2,2',3'-Tetrafluoroacetophenone exported by TSS?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 2,2',3'-Tetrafluoroacetophenone.
How can I request a sample or quote for 2,2',3'-Tetrafluoroacetophenone?
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Please contact the Tech Serve Solutions sales team via our website or direct email to request a sample or a quotation for 2,2',3'-Tetrafluoroacetophenone.
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