2,2,2,3′,4′-Pentafluoroacetophenone
2,2,2,3′,4′-Pentafluoroacetophenone (CAS: 302912-28-3) is a fluorinated ketone with the molecular formula C7H3F5O and a molecular weight of 210.10. This compound serves as a valuable building block in organic synthesis, particularly in the development of novel fluorinated molecules. Its trifluoromethyl and pentafluorophenyl groups offer unique reactivity and properties, making it a key intermediate in research and development across various chemical sectors.
- Synonyms
- 3′,4′-PentafluoroacetophenoneF2C6H3COCF3

Organic Synthesis Intermediate
Used as a versatile building block for the synthesis of complex organic molecules. Its fluorinated structure allows for the introduction of specific properties into target compounds.
Fluorinated Compound Development
Essential in research for creating new fluorinated materials, pharmaceuticals, and agrochemicals where fluorine incorporation is desired for enhanced efficacy or stability.
Chemical Research Reagent
Employed in academic and industrial laboratories for exploring new reaction pathways and developing innovative chemical entities.
| Molecular weight | 210.10 |
|---|---|
| Linear formula | F2C6H3COCF3 |
| Assay | 95% |
| Boiling point | 150 °C(lit.) |
| Density | 1.464 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.4375(lit.) |

Hazard statements
- H226Flammable liquid and vapour
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 51 °C / 123.8 °F |
| Transport (UN / ADR) | UN 1993C 3 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Risk statements (R) | 10 |
| Safety statements (S) | 16 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,2,2,3′,4′-Pentafluoroacetophenone used for?
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2,2,2,3′,4′-Pentafluoroacetophenone is primarily used as a building block in organic synthesis for the development of novel fluorinated compounds, including pharmaceuticals and materials.
What are the CAS number and formula for this compound?
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The CAS number is 302912-28-3 and the molecular formula is C7H3F5O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2,2,2,3′,4′-Pentafluoroacetophenone with an assay of 95%. This product is intended for research and laboratory use and is not represented as USP, BP, EP, or any other pharmacopoeia grade.
How should 2,2,2,3′,4′-Pentafluoroacetophenone be handled safely?
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This compound is a flammable liquid and vapour (H226). Handle with appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator, in a well-ventilated area. Store away from heat and ignition sources.
How is 2,2,2,3′,4′-Pentafluoroacetophenone packed, shipped, and exported?
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2,2,2,3′,4′-Pentafluoroacetophenone is packed according to relevant shipping regulations for flammable liquids. Tech Serve Solutions is an experienced global supplier and exporter of fine chemicals.
How can I request a sample or quote for 2,2,2,3′,4′-Pentafluoroacetophenone?
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To request a sample or a quote, please contact our sales department via the details provided on our website.
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