cis-4-Hydroxy-D-proline
cis-4-Hydroxy-D-proline (CAS: 2584-71-6, C5H9NO3) is a non-proteinogenic amino acid and a modified derivative of proline. This compound is recognised for its structural role in collagen and its utility as a chiral building block in organic synthesis. Tech Serve Solutions supplies this high-purity reagent for applications in chemical biology, peptide chemistry, and the development of novel pharmaceutical intermediates.
- IUPAC
- (2R,4R)-(+)-4-Hydroxy-2-pyrrolidinecarboxylic acid,D-allo-Hydroxyproline
- Synonyms
- D-allo-Hydroxyproline

Peptide Synthesis
Used as a modified amino acid in the synthesis of peptides and peptidomimetics, introducing specific structural constraints and properties.
Chiral Building Block
Serves as a valuable chiral synthon in the asymmetric synthesis of complex organic molecules and pharmaceutical agents.
Biochemical Research
Employed in studies related to collagen structure, protein folding, and as a reagent in chemical biology investigations.
Pharmaceutical Intermediate
Acts as a precursor or intermediate in the synthesis pathway for various active pharmaceutical ingredients (APIs).
| Molecular weight | 131.13 |
|---|---|
| Empirical formula | C5H9NO3 |
| Assay | 98% |
| Grade | Vetec™ reagent grade |
| Melting point | 243 °C (dec.)(lit.) |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is cis-4-Hydroxy-D-proline used for?
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cis-4-Hydroxy-D-proline is primarily used in peptide synthesis, as a chiral building block in organic synthesis, and in biochemical research, particularly concerning collagen and protein structure.
What are the CAS number and molecular formula for cis-4-Hydroxy-D-proline?
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The CAS number is 2584-71-6 and the molecular formula is C5H9NO3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies cis-4-Hydroxy-D-proline in Vetec™ reagent grade with an assay of 98%. TSS does not represent this product as USP, BP, EP, or other pharmacopoeia grades unless explicitly stated.
How should cis-4-Hydroxy-D-proline be handled and stored?
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cis-4-Hydroxy-D-proline has a high melting point (243 °C dec.). Handle with appropriate personal protective equipment in a well-ventilated area. Refer to the Safety Data Sheet (SDS) for detailed hazard information and storage recommendations, noting its WGK Germany classification of 3.
How is cis-4-Hydroxy-D-proline packed, shipped, and exported?
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Products are carefully packed to ensure integrity during transit. Tech Serve Solutions is experienced in global shipping and export of fine chemicals, adhering to all relevant regulations.
How can I request a sample or quote for cis-4-Hydroxy-D-proline?
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Please contact our sales team through the website or by phone to request a sample or a detailed quotation for cis-4-Hydroxy-D-proline.
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