2,2,2,4′-Tetrafluoroacetophenone
2,2,2,4′-Tetrafluoroacetophenone (CAS: 655-32-3) is an organic fluorinated building block with the molecular formula C<sub>8</sub>H<sub>4</sub>F<sub>4</sub>O and a molecular weight of 192.11 g/mol. This ketone features a trifluoromethyl group and a para-fluorinated phenyl ring. It is primarily utilised in chemical synthesis as a versatile intermediate for the creation of more complex organic molecules, particularly those incorporating fluorine.
- IUPAC
- α,α,α,4-Tetrafluoroacetophenone
- Synonyms
- 4′-Tetrafluoroacetophenoneα,α,α,4-Tetrafluoroacetophenone
Fluorinated Organic Synthesis
Serves as a key intermediate in the synthesis of novel fluorinated organic compounds. Its structure allows for various chemical transformations, making it valuable for developing new materials and active pharmaceutical ingredients.
Research and Development
Employed in research laboratories for the exploration of new synthetic routes and the development of fluorinated compounds with potential applications in diverse scientific fields, including medicinal chemistry and material science.
Building Block for Complex Molecules
Functions as a crucial building block in multi-step syntheses, enabling the introduction of both a carbonyl group and a trifluoromethyl moiety into target structures.
| Molecular weight | 192.11 |
|---|---|
| Linear formula | FC6H4COCF3 |
| Assay | 99% |
| Boiling point | 66-67 °C/34 mmHg(lit.) |
| Density | 1.37 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.448(lit.) |
| Melting point | 24-27 °C(lit.) |
Hazard statements
- H228Flammable solid
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Flash point | 32 °C / 89.6 °F |
| Transport (UN / ADR) | UN 1325 4.1 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xi |
| Risk statements (R) | 11-36/37/38 |
| Safety statements (S) | 16-26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,2,2,4′-Tetrafluoroacetophenone used for?
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2,2,2,4′-Tetrafluoroacetophenone is primarily used as a building block in organic synthesis, particularly for the creation of more complex fluorinated organic molecules and in research and development.
What is the CAS number and formula for 2,2,2,4′-Tetrafluoroacetophenone?
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The CAS number is 655-32-3 and the linear formula is FC<sub>6</sub>H<sub>4</sub>COCF<sub>3</sub>.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2,2,2,4′-Tetrafluoroacetophenone with a minimum assay of 99%. This product is not represented as USP, BP, EP, or any other pharmacopoeia grade.
How should 2,2,2,4′-Tetrafluoroacetophenone be handled safely?
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2,2,2,4′-Tetrafluoroacetophenone is a flammable solid and is hazardous. It causes skin irritation, serious eye irritation, and may cause respiratory irritation. Appropriate personal protective equipment, including eyeshields, gloves, and suitable respiratory protection, must be used. Store away from ignition sources and handle in a well-ventilated area.
How is 2,2,2,4′-Tetrafluoroacetophenone packed, shipped, and exported?
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Tech Serve Solutions ensures appropriate packaging for safe transport and handles export procedures in compliance with international regulations.
How can I request a sample or a quote for 2,2,2,4′-Tetrafluoroacetophenone?
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Please contact our sales team via the website or telephone to request a sample or a quotation.
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