2,2,2-Trichloroethoxysulfonamide
2,2,2-Trichloroethoxysulfonamide (CAS 69226-51-3), with the empirical formula C2H4Cl3NO3S and a molecular weight of 228.48, is a specialized chemical building block. It serves as a nitrogen source in intermolecular rhodium-catalyzed C-H amination reactions. This compound is a valuable reagent in organic synthesis, particularly for researchers in cell biology and chemical synthesis requiring precise molecular construction.
- IUPAC
- 2,2,2-Trichloroethyl sulfamate,Sulfamic acid, 2,2,2-trichloroethyl ester
- Synonyms
- 69226-51-3, C2H4Cl3NO3S, 2,2,2-Trichloroethyl sulfamate, Sulfamic acid, 2,2,2-trichloroethyl ester

Intermolecular C-H Amination
Utilized as a nitrogen source in rhodium-catalyzed intermolecular amination of C-H bonds. This application is crucial for forming new carbon-nitrogen bonds in complex organic molecules.
Organic Synthesis Building Block
Serves as a versatile building block for constructing more complex organic molecules. Its unique structure lends itself to various synthetic pathways in research and development.
Chemical Research Reagent
A valuable reagent for academic and industrial research laboratories engaged in exploring novel chemical transformations and synthesizing new chemical entities.
| Molecular weight | 228.48 |
|---|---|
| Empirical formula | C2H4Cl3NO3S |
| Assay | 97% |
| Application | Nitrogen source in an intermolecular rhodium-catalyzed (662623) amination of C-H bonds.1 |
| Melting point | 52-58 °C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Flash point | >110 °C / >230 °F |
| Water hazard class (WGK, DE) | 2 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... STS(412) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,2,2-Trichloroethoxysulfonamide used for?
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2,2,2-Trichloroethoxysulfonamide is primarily used as a nitrogen source in intermolecular rhodium-catalyzed amination of C-H bonds and as a building block in organic synthesis.
What is the CAS number and molecular formula for 2,2,2-Trichloroethoxysulfonamide?
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The CAS number is 69226-51-3, and the empirical formula (Hill notation) is C2H4Cl3NO3S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2,2,2-Trichloroethoxysulfonamide with a purity of 97%. This product is supplied for research and development purposes and is not represented as USP, BP, or EP grade.
What are the safety and handling precautions for 2,2,2-Trichloroethoxysulfonamide?
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Handling requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used. The compound has a WGK Germany classification of 2, indicating it is hazardous to water.
How is 2,2,2-Trichloroethoxysulfonamide packed, shipped, and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, ensuring appropriate packaging and adherence to international shipping regulations for chemicals like 2,2,2-Trichloroethoxysulfonamide.
How can I request a quote or sample for 2,2,2-Trichloroethoxysulfonamide?
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Please contact our sales team directly via the website or by phone to request a quote or a sample of 2,2,2-Trichloroethoxysulfonamide.
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