(1S)-(−)-Camphanic chloride
(1S)-(−)-Camphanic chloride (CAS 39637-74-6, C10H13O3Cl) is a chiral acid halide and an organic building block. With a molecular weight of 216.66 g/mol, it is primarily utilised in asymmetric synthesis for the preparation of enantiomerically pure compounds. This chemical serves as a valuable intermediate in complex organic syntheses, contributing to the development of pharmaceuticals and other fine chemicals.
- IUPAC
- (−)-Camphanoyl chloride,(1S)-3-Oxo-4,7,7-trimethyl-2-oxabicyclo[2.2.1]heptane-1-carbonyl chloride
- Synonyms
- (−)-Camphanoyl chloride(1S)-3-Oxo-4,7,7-trimethyl-2-oxabicyclo[2.2.1]heptane-1-carbonyl chloride
Chiral Building Block in Organic Synthesis
This compound is a key chiral intermediate used to introduce specific stereochemistry into target molecules. Its structure facilitates its use in the synthesis of complex organic structures where enantiomeric purity is critical.
Asymmetric Synthesis Applications
(1S)-(−)-Camphanic chloride is employed in asymmetric synthesis methodologies to create chiral derivatives. It enables the controlled formation of stereocenters, crucial for the production of optically active compounds.
Pharmaceutical Intermediate
The compound serves as a precursor in the multi-step synthesis of active pharmaceutical ingredients (APIs). Its chiral nature is important for developing stereospecific drugs.
| Molecular weight | 216.66 |
|---|---|
| Linear formula | C10H13O3Cl |
| Assay | 98% |
| Optical activity | [α]23/D −18°, c = 2 in carbon tetrachloride |
| Optical purity | ee: 99% (GLC) |
| Storage temperature | 2-8°C |
| Melting point | 71-73 °C(lit.) |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 3261 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (1S)-(−)-Camphanic chloride used for?
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(1S)-(−)-Camphanic chloride is used as a chiral building block and intermediate in asymmetric synthesis, particularly for the preparation of enantiomerically pure compounds and in pharmaceutical synthesis.
What is the CAS number and chemical formula for (1S)-(−)-Camphanic chloride?
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The CAS number is 39637-74-6 and the chemical formula is C10H13O3Cl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (1S)-(−)-Camphanic chloride with an assay of 98%. We do not represent this product as USP, BP, or EP grade.
How should (1S)-(−)-Camphanic chloride be handled safely?
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(1S)-(−)-Camphanic chloride is a danger to health, causing severe skin burns and eye damage (H314). Appropriate personal protective equipment including eyeshields, face shields, gloves, and respiratory protection (e.g., N100 respirator) must be used. Handle only in a well-ventilated area.
How is (1S)-(−)-Camphanic chloride packed and shipped?
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This product is shipped as a hazardous material under UN 3261, 8, PGII. Specific packaging requirements are met to ensure safe transportation and export compliance.
How can I request a sample or quote for (1S)-(−)-Camphanic chloride?
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To request a sample or obtain a quotation, please contact our sales department with your specific requirements.
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