(1R,4S)-(+)-4-(Fmoc-amino)-2-cyclopentene-1-carboxylic acid
(1R,4S)-(+)-4-(Fmoc-amino)-2-cyclopentene-1-carboxylic acid (CAS: 220497-65-4), with a molecular formula of C21H19NO4 and a molecular weight of 349.38 g/mol, is a valuable chiral building block. This unnatural amino acid derivative finds utility in advanced chemical synthesis and peptide chemistry. Its unique structure facilitates the introduction of non-proteinogenic amino acid residues into peptide chains, offering novel structural and functional properties for research and development.
- Synonyms
- C21H19NO4
Peptide Synthesis
Incorporation into peptide sequences to create peptidomimetics or peptides with modified structures and enhanced biological activity. The Fmoc protecting group allows for straightforward solid-phase peptide synthesis.
Chemical Biology Research
Serves as a probe or tool compound for investigating biological pathways or protein-ligand interactions. Its alicyclic structure can impart unique conformational constraints.
Asymmetric Synthesis
Utilised as a chiral precursor or intermediate in the synthesis of complex organic molecules, pharmaceuticals, and natural products where stereochemical control is critical.
Drug Discovery and Development
Acts as a scaffold for building novel molecular entities with potential therapeutic applications. Can be modified to explore structure-activity relationships.
| Molecular weight | 349.38 |
|---|---|
| Empirical formula | C21H19NO4 |
| Assay | ≥97.0% (sum of enantiomers, HPLC) |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (1R,4S)-(+)-4-(Fmoc-amino)-2-cyclopentene-1-carboxylic acid used for?
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This compound is primarily used as a chiral building block in chemical synthesis, particularly in peptide chemistry and chemical biology research for creating novel peptides, peptidomimetics, and complex organic molecules.
What is the CAS number and molecular formula for this chemical?
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The CAS number is 220497-65-4 and the molecular formula is C21H19NO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product with an assay of ≥97.0% (sum of enantiomers, HPLC). We do not represent this product as USP, BP, EP, or other pharmacopoeial grades unless explicitly stated in the product data.
How should (1R,4S)-(+)-4-(Fmoc-amino)-2-cyclopentene-1-carboxylic acid be handled and stored?
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Handle with appropriate personal protective equipment, including eyeshields and gloves. A respirator filter suitable for N95 (US) or P1 (EN143) is recommended. Store at 2-8°C.
Is this chemical shipped internationally?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals.
How can I request a sample or a quote?
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Please contact our sales team via the website or direct inquiry to request a sample or a quotation for (1R,4S)-(+)-4-(Fmoc-amino)-2-cyclopentene-1-carboxylic acid.
Does this product have any special handling requirements due to its hazard classification?
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This chemical has a WGK Germany classification of 3, indicating it is hazardous to water. Handle and dispose of it responsibly, avoiding release into the environment.
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