(1R,4R)-Bicyclo[2.2.2]octane-2,5-dione
(1R,4R)-Bicyclo[2.2.2]octane-2,5-dione (CAS: 76478-53-0) is a chiral organic compound with the molecular formula C8H10O2 and a molecular weight of 138.16 g/mol. This diketone serves as a valuable building block in asymmetric synthesis and general chemical synthesis. Its rigid bicyclic structure makes it useful for creating complex stereochemistries in various organic molecules, particularly in research and development settings.
- Synonyms
- 76478-53-0C8H10O2
![(1R,4R)-Bicyclo[2.2.2]octane-2,5-dione (C8H10O2) — chemical structure, CAS 76478-53-0; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F76478-53-0.png&w=3840&q=75)
Asymmetric Synthesis
(1R,4R)-Bicyclo[2.2.2]octane-2,5-dione is employed as a chiral building block in asymmetric synthesis, facilitating the creation of enantiomerically pure compounds. Its structure can impart specific stereochemical outcomes in complex organic transformations.
Chemical Synthesis Intermediate
This diketone functions as a versatile intermediate in various organic synthesis pathways. Researchers utilise its bicyclic framework to construct novel molecular architectures and explore new chemical reactions.
Chiral Pool Reagent
As a component of the chiral pool, (1R,4R)-Bicyclo[2.2.2]octane-2,5-dione offers a defined stereochemical starting point for the synthesis of chiral targets. It is instrumental in developing stereoselective synthetic routes.
| Molecular weight | 138.16 |
|---|---|
| Empirical formula | C8H10O2 |
| Assay | 95% |
| Optical activity | [α]22/D −53.0°, c = 0.5 in chloroform |
| Melting point | 202-206 °C |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H318Causes serious eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-37/38-41 |
| Safety statements (S) | 26-39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (1R,4R)-Bicyclo[2.2.2]octane-2,5-dione used for?
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This compound is primarily used as a chiral building block in asymmetric synthesis and as an intermediate in general chemical synthesis for creating complex stereochemistries.
What is the CAS number and molecular formula for (1R,4R)-Bicyclo[2.2.2]octane-2,5-dione?
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The CAS number is 76478-53-0 and the molecular formula is C8H10O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (1R,4R)-Bicyclo[2.2.2]octane-2,5-dione with an assay of 95%. This product is not represented as USP, BP, or EP grade.
How should (1R,4R)-Bicyclo[2.2.2]octane-2,5-dione be handled safely?
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Handle with appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves. Avoid dust formation and breathing dust. It is corrosive and may cause serious eye damage. Refer to the Safety Data Sheet for full details.
Is (1R,4R)-Bicyclo[2.2.2]octane-2,5-dione a controlled substance?
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The provided data does not indicate that (1R,4R)-Bicyclo[2.2.2]octane-2,5-dione is a controlled substance.
How is this chemical packed and shipped by TSS?
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Tech Serve Solutions ensures proper packaging for export, adhering to international shipping regulations for chemicals. Specific packing details can be provided upon request.
How can I request a quote or sample?
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To request a quote or a sample of (1R,4R)-Bicyclo[2.2.2]octane-2,5-dione, please contact our sales team through the website or direct email.
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