(1R,4S)-(+)-4-(Boc-amino)-2-cyclopentene-1-carboxylic acid
(1R,4S)-(+)-4-(Boc-amino)-2-cyclopentene-1-carboxylic acid (CAS: 151907-80-1; C11H17NO4; MW: 227.26) is a chiral, unnatural amino acid derivative. It features a Boc-protected amine and a carboxylic acid on a cyclopentene ring. This compound is valuable in chemical synthesis and peptide chemistry, serving as a building block for more complex molecules and peptidomimetics. Its defined stereochemistry makes it useful in chiral pool synthesis and chemical biology research.
- Synonyms
- (1R,4S)-(+)-4-(tert-Butoxycarbonylamino)-2-cyclopentene-1-carboxylic acid
Chemical Synthesis Building Block
Utilised as a chiral synthon for constructing complex organic molecules. Its functional groups allow for diverse derivatisation in multi-step syntheses.
Peptide Chemistry
Incorporated into peptide sequences to create modified peptides or peptidomimetics. It can introduce conformational constraints or novel functionalities.
Chemical Biology Research
Serves as a tool for investigating biological processes where unnatural amino acids are required. Aids in probing protein structure and function.
Unnatural Amino Acid Derivatives
A key intermediate for the synthesis of a variety of non-proteinogenic amino acids with specific structural properties for research applications.
| Molecular weight | 227.26 |
|---|---|
| Empirical formula | C11H17NO4 |
| Assay | ≥98.0% (HPLC) |
| Optical activity | [α]20/D +48.5±2°, c = 1% in methanol |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (1R,4S)-(+)-4-(Boc-amino)-2-cyclopentene-1-carboxylic acid used for?
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This compound is primarily used as a building block in chemical synthesis, particularly in peptide chemistry and for creating unnatural amino acid derivatives for chemical biology research.
What is the CAS number and formula for this compound?
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The CAS number is 151907-80-1 and the empirical formula is C11H17NO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical with an assay of ≥98.0% by HPLC. It is not supplied as USP, BP, EP, or any other pharmacopoeia grade.
What are the safety and handling precautions for this chemical?
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This compound is a Warning substance, causing skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Users should wear Eyeshields, Gloves, and a dust mask type N95 (US). Handle in a well-ventilated area and avoid breathing dust.
How is this chemical packed and shipped?
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Tech Serve Solutions packs and exports chemicals according to international shipping regulations. Specific packaging details are available upon request.
How can I request a sample or a quote?
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To request a sample or a quote for (1R,4S)-(+)-4-(Boc-amino)-2-cyclopentene-1-carboxylic acid, please contact our sales department via the website or by phone.
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