(1R,2S)-(−)-trans-2-(Aminomethyl)cyclohexanol
(1R,2S)-(−)-trans-2-(Aminomethyl)cyclohexanol (CAS: 133269-86-0) is a chiral amino alcohol with the molecular formula C7H15NO and a molecular weight of 129.20 g/mol. This compound serves as a valuable building block in asymmetric synthesis and general organic chemical synthesis. Its specific stereochemistry makes it particularly useful for creating complex chiral molecules, contributing to advancements in pharmaceutical and fine chemical research and development.
- Synonyms
- (1R,2S)-(−)-trans-2-(Aminomethyl)cyclohexanol

Chiral Building Block
Utilised in asymmetric synthesis to construct enantiomerically pure compounds. Its defined stereochemistry is crucial for introducing chirality in complex molecular architectures.
Pharmaceutical Intermediate
Serves as a key intermediate in the synthesis of active pharmaceutical ingredients (APIs). Its structure can be incorporated into drug candidates requiring specific stereochemical configurations.
Organic Synthesis Reagent
Employed as a versatile reagent in various organic transformations. Facilitates the development of novel compounds and materials in academic and industrial research.
| Molecular weight | 129.20 |
|---|---|
| Empirical formula | C7H15NO |
| Assay | ≥96.5% (GC)97% |
| Optical purity | enantiomeric excess: ≥97.5% |
| Storage temperature | 2-8°C |

Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 3259PSN1 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (1R,2S)-(−)-trans-2-(Aminomethyl)cyclohexanol used for?
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(1R,2S)-(−)-trans-2-(Aminomethyl)cyclohexanol is primarily used as a chiral building block in asymmetric synthesis and as an intermediate in the synthesis of complex organic molecules, including pharmaceuticals.
What is the CAS number and formula for (1R,2S)-(−)-trans-2-(Aminomethyl)cyclohexanol?
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The CAS number is 133269-86-0, and the empirical formula (Hill Notation) is C7H15NO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (1R,2S)-(−)-trans-2-(Aminomethyl)cyclohexanol with an assay of ≥96.5% (GC) or 97%, and an enantiomeric excess of ≥97.5%. This is a research/technical grade product and is not supplied as USP, BP, EP, or pharmaceutical grade.
How should (1R,2S)-(−)-trans-2-(Aminomethyl)cyclohexanol be handled safely?
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This compound is classified as Danger (GHS05) and causes severe skin burns and eye damage (H314). Appropriate personal protective equipment, including eyeshields, face shields, gloves, and respiratory protection (e.g., N100 or P3 filters), must be used. Handle in a well-ventilated area.
Is (1R,2S)-(−)-trans-2-(Aminomethyl)cyclohexanol a controlled substance?
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Based on the provided data, there is no indication that (1R,2S)-(−)-trans-2-(Aminomethyl)cyclohexanol is a controlled substance.
How is this chemical shipped and exported by Tech Serve Solutions?
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This chemical is shipped and exported according to relevant dangerous goods regulations, identified under UN 3259, PSN1 8, PGII.
How can I request a sample or quote for (1R,2S)-(−)-trans-2-(Aminomethyl)cyclohexanol?
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To request a sample or a quote, please contact our sales department through the website or by phone, providing the product name and CAS number (133269-86-0).
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