(1R,2S)-1-[(3,5-Di-tert-butyl-2-hydroxybenzylidene)amino]-2-indanol
(1R,2S)-1-[(3,5-Di-tert-butyl-2-hydroxybenzylidene)amino]-2-indanol (CAS: 275374-67-9) is a chiral organic compound with the molecular formula C24H31NO2. This high-purity chemical, assaying at 97%, serves as a valuable ligand in asymmetric synthesis. It is particularly recognised for its application in vanadium-catalyzed oxidation reactions, notably the oxidation of sulfides using hydrogen peroxide.
- IUPAC
- (1R,2S)-1-((2-Hydroxy-3,5-di-tert-butylbenzylidene)amino)indan-2-ol
- Synonyms
- 275374-67-9C24H31NO2
![(1R,2S)-1-[(3,5-Di-tert-butyl-2-hydroxybenzylidene)amino]-2-indanol (C24H31NO2) — chemical structure, CAS 275374-67-9; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F275374-67-9.png&w=3840&q=75)
Asymmetric Synthesis
This compound functions as a chiral ligand in asymmetric synthesis, enabling stereoselective transformations. Its structure facilitates the formation of chiral products with high enantiomeric purity.
Vanadium-Catalyzed Oxidation
It is employed in vanadium-catalyzed oxidation processes, specifically for the oxidation of sulfides. In these reactions, it works in conjunction with hydrogen peroxide as the oxidant.
Ligand in Catalysis
As a chiral ligand, it plays a crucial role in metal-catalyzed reactions, influencing the stereochemical outcome. Its coordination properties are key to its efficacy in stereoselective catalysis.
| Molecular weight | 365.51 |
|---|---|
| Empirical formula | C24H31NO2 |
| Assay | 97% |
| Optical activity | [α]20/D +32°, c = 0.5% in methylene chloride |
| Application | Used in the vanadium-catalyzed oxidation of sulfides in conjunction with hydrogen peroxide.1 |
| Melting point | 128-133 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (1R,2S)-1-[(3,5-Di-tert-butyl-2-hydroxybenzylidene)amino]-2-indanol used for?
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(1R,2S)-1-[(3,5-Di-tert-butyl-2-hydroxybenzylidene)amino]-2-indanol is primarily used as a chiral ligand in asymmetric synthesis, particularly in vanadium-catalyzed oxidation reactions of sulfides.
What are the CAS number and molecular formula for this compound?
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The CAS number is 275374-67-9, and the molecular formula is C24H31NO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound at a minimum purity of 97%. This is considered a research or technical grade; TSS does not represent it as USP, BP, or EP grade.
How should this chemical be handled?
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This chemical is classified as a Warning, with hazards including skin irritation (H315), eye irritation (H319), and respiratory irritation (H335). Appropriate personal protective equipment, including a dust mask (N95), eyeshields, and gloves, should be used during handling. Avoid breathing dust.
Is this product available for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including this product.
How can I request a sample or a quote?
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Please contact our sales department via the website or direct inquiry to request a sample or obtain a quotation for this product.
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