11-Maleimidoundecanoic acid
11-Maleimidoundecanoic acid (CAS 57079-01-3; C15H23NO4) is a versatile organic compound with a molecular weight of 281.35 g/mol. It features a reactive maleimide group and a long alkyl chain terminating in a carboxylic acid. This dual functionality makes it valuable in materials science and polymer chemistry for conjugating biomolecules to polymer backbones, enabling advanced applications in bioconjugation and surface modification.
- IUPAC
- MUDA, Maleimidoundecanoic acid,11-Maleimide undecanoic acid,2,5-Dihydro-2,5-dioxo-1H-pyrrole-1-undecanoic acid,MM-281
Bioconjugation Agent
The maleimide moiety readily reacts with thiol groups found in cysteine residues of proteins and peptides, allowing for the covalent attachment of biomolecules. This is crucial for developing antibody-drug conjugates, diagnostic assays, and functionalised biomaterials.
Polymer Modification
11-Maleimidoundecanoic acid can be incorporated into polymer chains to introduce pendant maleimide groups. These functionalised polymers can then be crosslinked or modified with thiol-containing molecules to tailor material properties for specific applications.
Surface Functionalisation
The carboxylic acid group enables anchoring to surfaces (e.g., nanoparticles or sensor platforms), while the maleimide group allows for subsequent attachment of biomolecules or other functional moieties, creating tailored interfaces.
| Molecular weight | 281.35 |
|---|---|
| Empirical formula | C15H23NO4 |
| Assay | 95% (GC) |
| Form | powder |
| Application | The maleimide functional group can be used to conjugate a variety of biomolecules such as enzymes1 and DNA2 to the polymer chain. |
| Melting point | 94-98 °C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 11-Maleimidoundecanoic acid used for?
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11-Maleimidoundecanoic acid is used in bioconjugation to attach biomolecules like enzymes and DNA to polymer chains, and for polymer modification and surface functionalisation.
What is the CAS number and formula for 11-Maleimidoundecanoic acid?
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The CAS number is 57079-01-3 and the empirical formula is C15H23NO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 11-Maleimidoundecanoic acid with an assay of 95% (GC). This product is not represented as USP, BP, or EP grade.
How should 11-Maleimidoundecanoic acid be handled?
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Warning: Causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Handle with appropriate personal protective equipment in a well-ventilated area. Avoid breathing dust.
Is 11-Maleimidoundecanoic acid a controlled substance?
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Based on the provided data, 11-Maleimidoundecanoic acid is not indicated as a controlled substance.
How is 11-Maleimidoundecanoic acid packed and exported by TSS?
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Tech Serve Solutions, a global supplier and exporter since 1998, securely packs and exports fine chemicals including 11-Maleimidoundecanoic acid to meet international shipping regulations.
How can I request a quote or sample of 11-Maleimidoundecanoic acid?
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Please contact our sales team or use the online enquiry form on the TSS website to request a quote or sample of 11-Maleimidoundecanoic acid.
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