1-Naphthylmagnesium bromide solution
1-Naphthylmagnesium bromide solution (CAS: 703-55-9, Molecular Weight: 231.37) is a highly reactive organometallic reagent. Supplied as a 0.25 M slurry in THF, it is an essential tool in organic synthesis. This Grignard reagent is primarily utilised for introducing the 1-naphthyl group into various organic molecules, facilitating the construction of complex molecular architectures in research and development settings. Its utility spans diverse synthetic transformations.
Organic Synthesis Intermediate
1-Naphthylmagnesium bromide serves as a key intermediate in the synthesis of complex organic compounds. It readily participates in nucleophilic addition and substitution reactions to form new carbon-carbon bonds.
Aryl Group Introduction
This Grignard reagent is specifically employed for the efficient introduction of the 1-naphthyl moiety onto electrophilic substrates, enabling the synthesis of naphthyl-containing pharmaceuticals, agrochemicals, and materials.
Research and Development
Utilised in academic and industrial research laboratories for exploring novel synthetic routes and developing new chemical entities. Its reactivity profile makes it valuable for specialised chemical transformations.
| Molecular weight | 231.37 |
|---|---|
| Empirical formula | C10H7BrMg |
| Boiling point | 65 °C |
| Density | 0.908 g/mL at 25 °C |
| Concentration | 0.25 M slurry in THF |
Hazard statements
- H225Highly flammable liquid and vapour
- H314Causes severe skin burns and eye damage
- H335May cause respiratory irritation
- H351Suspected of causing cancer
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Flash point | -17 °C / 1.4 °F |
|---|---|
| Transport (UN / ADR) | UN 2924 8(3) / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xn |
| Risk statements (R) | 11-14-19-36/37/38-40 |
| Safety statements (S) | 16-26-36/37 |
| Supplemental hazards | May form explosive peroxides., Reacts violently with water. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-Naphthylmagnesium bromide solution used for?
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1-Naphthylmagnesium bromide solution is used as a Grignard reagent in organic synthesis, primarily for introducing the 1-naphthyl group into organic molecules. It is a valuable intermediate in the synthesis of complex organic compounds and for research and development purposes.
What are the CAS number and formula for 1-Naphthylmagnesium bromide solution?
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The CAS number is 703-55-9. The empirical formula is C10H7BrMg.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1-Naphthylmagnesium bromide solution as a 0.25 M slurry in THF. We do not represent this product as USP, BP, EP, or other pharmacopoeia grades unless explicitly stated in the product specifications.
How should 1-Naphthylmagnesium bromide solution be handled?
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This solution is highly flammable and reacts violently with water. It causes severe skin burns and eye damage, and may cause respiratory irritation. It is also suspected of causing cancer. Handle with extreme caution in a well-ventilated area, away from ignition sources, and wear appropriate personal protective equipment, including gloves, eye protection, and protective clothing. Refer to the Safety Data Sheet (SDS) for full handling instructions.
Is 1-Naphthylmagnesium bromide solution regulated?
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Based on the provided data, there is no explicit mention of controlled or scheduled substance status. However, its flammable and corrosive nature requires adherence to all relevant chemical handling and transport regulations.
How is 1-Naphthylmagnesium bromide solution packed, shipped, and exported?
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1-Naphthylmagnesium bromide solution is packed in UN-approved containers suitable for hazardous materials, conforming to transport regulations (UN 2924 8(3) / PGII). TSS is experienced in exporting fine chemicals globally, ensuring compliance with international shipping standards.
How can I request a sample or quote for 1-Naphthylmagnesium bromide solution?
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Please contact the Tech Serve Solutions sales team via our website or direct inquiry channels to request a sample or a formal quotation. Please specify the required quantity and delivery location.
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