1-Methylbutylzinc bromide solution
1-Methylbutylzinc bromide solution (CAS: 308796-07-8) is an organozinc halide supplied by Tech Serve Solutions (TSS) at a concentration of 0.5 M in THF. With a molecular weight of 216.43 g/mol and a density of 0.961 g/mL at 25°C, this flammable reagent is primarily utilised in organic synthesis. It serves as a valuable building block for introducing the 1-methylbutyl group into various organic structures, facilitating complex molecule construction.
Organozinc Reagent in Organic Synthesis
This compound acts as a nucleophilic source of the 1-methylbutyl group, enabling its introduction into organic molecules through cross-coupling reactions or addition to electrophiles. Its reactivity profile makes it suitable for the construction of complex carbon skeletons in multi-step syntheses.
Synthesis of Pharmaceutical Intermediates
1-Methylbutylzinc bromide can be employed in the stereoselective synthesis of chiral centres, a common requirement in the preparation of pharmaceutical intermediates. Its use allows for precise control over the introduction of branched alkyl chains.
Preparation of Specialty Chemicals
The reagent is applicable in the synthesis of fine and specialty chemicals where the 1-methylbutyl moiety is a key structural component. This includes applications in materials science and the development of novel organic compounds.
| Molecular weight | 216.43 |
|---|---|
| Linear formula | CH3CH2CH2CH(CH3)ZnBr |
| Density | 0.961 g/mL at 25 °C |
| Concentration | 0.5 M in THF |
| Storage temperature | 2-8°C |
Hazard statements
- H225Highly flammable liquid and vapour
- H319Causes serious eye irritation
- H335May cause respiratory irritation
- H351Suspected of causing cancer
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P281Use personal protective equipment as required
- P305IF IN EYES
| Flash point | -17 °C / 1.4 °F |
|---|---|
| Transport (UN / ADR) | UN 2924 8(3) / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xn |
| Risk statements (R) | 11-19-36/37-40 |
| Safety statements (S) | 16-26-36/37 |
| Supplemental hazards | May form explosive peroxides. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-Methylbutylzinc bromide solution used for?
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1-Methylbutylzinc bromide solution is primarily used as a reagent in organic synthesis for introducing the 1-methylbutyl group, particularly in the preparation of pharmaceutical intermediates and specialty chemicals.
What is the CAS number and formula for 1-Methylbutylzinc bromide solution?
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The CAS number is 308796-07-8. The linear formula is CH3CH2CH2CH(CH3)ZnBr.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product as a 0.5 M solution in THF. TSS does not represent this product as USP, BP, or EP grade.
How should 1-Methylbutylzinc bromide solution be handled?
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1-Methylbutylzinc bromide solution is a flammable liquid that may form explosive peroxides. It is also an irritant to the eyes and respiratory system and is suspected of causing cancer. Handle with appropriate personal protective equipment (gloves, eye protection) in a well-ventilated area, away from ignition sources.
How is 1-Methylbutylzinc bromide solution shipped?
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This product is shipped under UN 2924, Hazard Class 8 (Corrosive) with Subsidiary Hazard Class 3 (Flammable), Packing Group II. Storage is recommended at 2-8°C.
How can I request a sample or quote for 1-Methylbutylzinc bromide solution?
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Please contact Tech Serve Solutions directly via our website or sales representatives to request a sample or a quotation for 1-Methylbutylzinc bromide solution.
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