1-Methyl-L-histidine
1-Methyl-L-histidine (CAS: 332-80-9; Formula: C7H11N3O2; Molar Mass: 169.18 g/mol) is a methylated derivative of the amino acid histidine. It functions as a building block in certain biological processes and is utilised in chemical synthesis. This compound is essential for researchers investigating peptide chemistry, chemical biology, and related fields. TSS provides this high-quality reagent for laboratory and research applications.
- IUPAC
- 3-(1-Methylimidazol-4-yl)-L-alanine,3-Methyl-L-histidine (archaic),Nτ-Methyl-L-histidine
- Synonyms
- 3-(1-Methylimidazol-4-yl)-L-alanine3-Methyl-L-histidine (archaic)Nτ-Methyl-L-histidine
Chemical Synthesis
1-Methyl-L-histidine serves as a valuable intermediate or building block in the synthesis of more complex organic molecules and peptides. Its specific structure allows for targeted modifications in synthetic routes.
Chemical Biology Research
This compound is employed in studies within chemical biology, particularly for understanding enzymatic reactions, protein modifications, and metabolic pathways involving histidine derivatives.
Peptide Chemistry
As a modified amino acid, 1-Methyl-L-histidine is utilised in peptide synthesis to introduce specific properties or to study the effects of methylation on peptide structure and function.
| Molecular weight | 169.18 |
|---|---|
| Empirical formula | C7H11N3O2 |
| Assay | ≥98.0% (TLC) |
| Optical activity | [α]20/D −24±1°, c = 2% in H2O |
| Impurities tested | ≤5% water |
| Melting point | ~240 °C (dec.)(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-Methyl-L-histidine used for?
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1-Methyl-L-histidine is used in chemical synthesis, chemical biology research, and peptide chemistry as a modified amino acid building block.
What is the CAS number and formula for 1-Methyl-L-histidine?
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The CAS number is 332-80-9 and the empirical formula is C7H11N3O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1-Methyl-L-histidine with an assay of ≥98.0% (TLC) and ≤5% water. This is a research-grade chemical and is not supplied as USP, BP, EP, or pharmaceutical grade.
How should 1-Methyl-L-histidine be handled?
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Handle 1-Methyl-L-histidine with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or P1 (EN143) respirator filter is recommended. Refer to the safety data sheet for detailed handling instructions.
Does Tech Serve Solutions export 1-Methyl-L-histidine?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 1-Methyl-L-histidine.
How can I request a sample or quote for 1-Methyl-L-histidine?
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Please contact our sales team through the website or by phone to request a sample or a quote for 1-Methyl-L-histidine.
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