1-Methyl-D-tryptophan
1-Methyl-D-tryptophan (CAS: 110117-83-4), with the molecular formula C12H14N2O2, is a derivative of the amino acid tryptophan. This compound serves as a valuable building block in organic synthesis, particularly in the preparation of natural products and complex indole structures. Its applications span chemical biology and peptide chemistry, facilitating the creation of novel molecular architectures.
Natural Product Synthesis
Used in the preparation of macroline alkaloids via the Pictet-Spengler reaction of tryptophan esters with aldehydes. This application highlights its utility in constructing complex, naturally occurring molecular frameworks.
Indole Derivative Synthesis
Serves as a precursor in the synthesis of 1-substituted indolactam derivatives. This role is critical for accessing diverse indole-based compounds with potential biological activities.
Chemical Biology Research
As a modified amino acid, it finds applications in chemical biology for probing biological pathways and developing new molecular probes or inhibitors.
| Molecular weight | 218.25 |
|---|---|
| Empirical formula | C12H14N2O2 |
| Assay | 95% |
| Optical activity | [α]22/D +12.4°, c = 2 in acetic acid |
| Application | Used to prepare a number of natural products including macroline alkaloids using the Pictet-Spengler reaction of tryptophan esters with aldehydes1 also used in the synthesis of 1-substituted indolactam precursors.2 |
| Melting point | 242-245 °C(lit.) |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-Methyl-D-tryptophan used for?
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1-Methyl-D-tryptophan is used in organic synthesis for the preparation of natural products, such as macroline alkaloids, and in the synthesis of 1-substituted indolactam precursors. It is also employed in chemical biology and peptide chemistry.
What are the CAS number and molecular formula for 1-Methyl-D-tryptophan?
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The CAS number for 1-Methyl-D-tryptophan is 110117-83-4, and its molecular formula is C12H14N2O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1-Methyl-D-tryptophan with an assay of 95%. This product is supplied for research and laboratory use. We do not represent it as USP, BP, EP, or any other pharmacopoeia grade.
What are the safety considerations for handling 1-Methyl-D-tryptophan?
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1-Methyl-D-tryptophan is classified as hazardous. It is harmful if swallowed and causes skin and eye irritation. Please refer to the Safety Data Sheet (SDS) for comprehensive handling, storage, and disposal information. Ensure appropriate personal protective equipment (PPE) is used.
How is 1-Methyl-D-tryptophan shipped?
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1-Methyl-D-tryptophan is carefully packed and exported by Tech Serve Solutions in compliance with international shipping regulations for chemicals.
How can I request a sample or quote for 1-Methyl-D-tryptophan?
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To request a sample or a quote for 1-Methyl-D-tryptophan, please contact our sales team through the website or by phone, providing your specific requirements.
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