1-Methyl-2-phenylindole
1-Methyl-2-phenylindole (CAS: 3558-24-5, C15H13N) is a heterocyclic organic compound with a molecular weight of 207.27. This indole derivative serves as a valuable reactant in various chemical syntheses, particularly for the preparation of substituted indoles. Its applications include the synthesis of cyano indoles and difluorohydroxy indoles, as well as facilitating carboxylation, allylation, formylation, and nitrosylation reactions of indole structures. Supplied by TSS with a typical assay of 99%, it is a key building block for advanced chemical research and development.
- IUPAC
- NSC 63793
Synthesis of Cyano Indoles
1-Methyl-2-phenylindole is a precursor for the synthesis of cyano indoles, which are important intermediates in organic chemistry. These compounds can be further modified for various applications.
Preparation of Difluorohydroxy Indoles
This compound is utilized in the preparation of difluorohydroxy indoles. The introduction of fluorine atoms can significantly alter the properties of organic molecules, making them useful in pharmaceutical and material science research.
Indole Carboxylation Reactions
1-Methyl-2-phenylindole acts as a reactant in the carboxylation of indoles. This process introduces a carboxyl group onto the indole ring, a crucial step in building more complex molecular structures.
Indole Allylation Reactions
The compound facilitates the allylation of indoles, a reaction that attaches an allyl group to the indole core. This transformation is vital for creating diverse organic frameworks.
Indole Formylation and Nitrosylation
1-Methyl-2-phenylindole is employed as a reactant in both formylation and nitrosylation reactions of indoles. These reactions introduce formyl or nitroso groups, respectively, expanding synthetic possibilities.
| Molecular weight | 207.27 |
|---|---|
| Empirical formula | C15H13N |
| Assay | 99% |
| Application | Reactant for preparation of: • Cyano indoles1• Difluorohydroxy indoles2Reactant for:• Carboxylation of indoles3• Allylation of indoles4• Formylation of indoles5• Nitrosylation of indoles5 |
| Melting point | 98-100 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-Methyl-2-phenylindole used for?
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1-Methyl-2-phenylindole (CAS: 3558-24-5) is used as a reactant in the preparation of various substituted indoles, including cyano indoles and difluorohydroxy indoles. It also serves as a reactant for carboxylation, allylation, formylation, and nitrosylation of indoles.
What are the CAS number and formula for 1-Methyl-2-phenylindole?
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The CAS number for 1-Methyl-2-phenylindole is 3558-24-5, and its empirical formula is C15H13N.
What grade and purity does Tech Serve Solutions supply for 1-Methyl-2-phenylindole?
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Tech Serve Solutions supplies 1-Methyl-2-phenylindole with a minimum assay of 99%. This is a technical/research grade chemical, and TSS does not represent it as USP, BP, EP, or any other pharmacopoeia grade.
How should 1-Methyl-2-phenylindole be handled safely?
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1-Methyl-2-phenylindole is classified as a Warning substance (GHS07) and may cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Handle with appropriate personal protective equipment, including gloves and eye protection, and ensure adequate ventilation. Avoid breathing dust/fume/gas/mist/vapours/spray. In case of contact with eyes, rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing. In case of inhalation, move the person to fresh air and keep them comfortable for breathing.
Is 1-Methyl-2-phenylindole a controlled substance?
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Based on the provided data, there is no indication that 1-Methyl-2-phenylindole (CAS: 3558-24-5) is a controlled substance.
How is 1-Methyl-2-phenylindole packed, shipped, and exported?
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Tech Serve Solutions expertly packs, ships, and exports 1-Methyl-2-phenylindole globally, adhering to all necessary regulations for chemical transport. Specific packaging details are available upon request.
How can I request a sample or quote for 1-Methyl-2-phenylindole?
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To request a sample or a quote for 1-Methyl-2-phenylindole, please contact our sales team directly through the TSS website or by phone. We are happy to assist with your specific requirements.
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