1-Methyl-2-oxindole
1-Methyl-2-oxindole (CAS: 61-70-1) is a heterocyclic organic compound with the molecular formula C9H9NO and a molecular weight of 147.17 g/mol. This indole derivative serves as a key building block in chemical synthesis. It is primarily utilised as a reactant in the preparation of a wide array of complex molecules, including potential therapeutic agents and biologically active compounds. Its utility spans the development of anticancer, antimalarial, and antiviral agents, as well as compounds influencing plant germination.
- IUPAC
- 1-Methyl-1,3-dihydroindol-2-one,1-Methyl-2-indolinone,1-Methyloxindole,Ba 2777,NSC 97219
Preparation of Novel Therapeutic Agents
1-Methyl-2-oxindole is employed as a reactant in the synthesis of various potential therapeutic compounds. This includes research into novel anticancer agents, antimalarial drugs, and compounds with potential applications in treating multiple sclerosis.
Development of Fluorescent Analogues
This compound is a precursor for creating fluorescent analogues of strigolactones. These analogues are investigated for their effects on parasitic weed germination and fungal branching, contributing to agricultural research.
Synthesis of Kinase Inhibitors
It serves as a reactant in the development of irreversible Nek2 Kinase Inhibitors. These inhibitors are of interest in biochemical research and the exploration of cellular signalling pathways.
Inducer of NAD(P)H-quinone Oxidoreductase 1 (NQO1)
1-Methyl-2-oxindole is used in the preparation of compounds that act as inducers of NAD(P)H-quinone oxidoreductase 1 (NQO1), an enzyme involved in cellular protection against oxidative stress.
| Molecular weight | 147.17 |
|---|---|
| Empirical formula | C9H9NO |
| Assay | 97% |
| Application | Reactant for preparation of:• Fluorescent analogues of strigolactones as affectors of parasitic weed germination and fungal branching1• Irreversible Nek2 Kinase Inhibitors2• Anticancer agents3• Antimalarial agents4• Antitimor agents5• Germination stimulants in plants6• Inducers of NAD(P)H-quinone oxidoreductase 1 (NQO1)7• Retinoic acid analogs8• Potential anti-multiple sclerosis agents9• Inhibitors of human immunodeficiency virus type 1 (HIV-1) integrase10 |
| Melting point | 85-88 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-Methyl-2-oxindole used for?
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1-Methyl-2-oxindole is used as a reactant in the chemical synthesis of various compounds, including fluorescent analogues, kinase inhibitors, anticancer agents, antimalarial agents, and germination stimulants in plants.
What are the CAS number and formula for 1-Methyl-2-oxindole?
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The CAS number for 1-Methyl-2-oxindole is 61-70-1, and its molecular formula is C9H9NO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1-Methyl-2-oxindole with a purity of 97%. This product is intended for research and laboratory use; TSS does not represent it as USP, BP, or EP grade.
How should 1-Methyl-2-oxindole be handled?
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1-Methyl-2-oxindole is a Warning substance that may cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Handle with appropriate personal protective equipment, including a dust mask type N95 (US), eyeshields, and gloves. Ensure adequate ventilation.
Is 1-Methyl-2-oxindole a controlled substance?
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The provided data does not indicate that 1-Methyl-2-oxindole (CAS: 61-70-1) is a controlled substance. For specific regulatory information, please consult relevant authorities.
How can I request a sample or quote for 1-Methyl-2-oxindole?
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To request a sample or a quote for 1-Methyl-2-oxindole, please use the contact form on our website or reach out to our sales team directly.
How is 1-Methyl-2-oxindole packed, shipped, and exported?
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1-Methyl-2-oxindole is carefully packed to ensure safe transit and is available for global export by Tech Serve Solutions. Specific packaging details are available upon request.
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