1-Bromo-4-(trimethylsiloxy)benzene
1-Bromo-4-(trimethylsiloxy)benzene (CAS: 17878-44-3, Formula: BrC6H4OSi(CH3)3) is a versatile organic compound with a molecular weight of 245.19 g/mol. This brominated aromatic silane serves as a valuable building block in organic synthesis and chemical research. Its protected phenolic hydroxyl group and reactive aryl bromide make it useful for introducing functionalised aromatic rings into more complex molecules. Available at 98% purity, it is suitable for various laboratory applications.
- IUPAC
- (4-Bromophenoxy)trimethylsilane
- Synonyms
- (4-Bromophenoxy)trimethylsilane
Organic Synthesis Intermediate
Used as a reagent in organic synthesis to construct complex molecular architectures. The trimethylsilyl protected phenol can be selectively deprotected, while the bromine atom allows for further functionalisation via cross-coupling reactions or Grignard formation.
Building Block for Fine Chemicals
A key intermediate in the synthesis of pharmaceuticals, agrochemicals, and materials science compounds. It allows for the precise introduction of a brominated, protected phenol moiety into target molecules.
Protecting Group Chemistry
The trimethylsilyl group acts as a protecting agent for the phenolic oxygen, enabling reactions to be carried out elsewhere on the molecule without affecting the hydroxyl group. It can be readily removed under mild conditions.
| Molecular weight | 245.19 |
|---|---|
| Linear formula | BrC6H4OSi(CH3)3 |
| Assay | 98% |
| Density | 1.268 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.515(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 97 °C / 206.6 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-Bromo-4-(trimethylsiloxy)benzene used for?
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1-Bromo-4-(trimethylsiloxy)benzene is primarily used as a versatile building block in organic synthesis, particularly for introducing a functionalised aromatic ring in the preparation of fine chemicals, pharmaceuticals, and materials.
What are the CAS number and chemical formula for this compound?
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The CAS number is 17878-44-3 and the linear chemical formula is BrC6H4OSi(CH3)3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1-Bromo-4-(trimethylsiloxy)benzene with an assay of 98%. We do not represent this product as USP, BP, EP, or any pharmacopoeia grade.
What are the main hazards associated with this chemical?
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This compound is classified as an irritant. It can cause skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including eye shields and gloves, should be used during handling.
How is this product packaged and shipped?
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1-Bromo-4-(trimethylsiloxy)benzene is carefully packaged to meet international shipping regulations. As a global supplier and exporter, TSS ensures compliant and secure dispatch for research and industrial needs.
How can I request a sample or quote?
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To request a sample or a quotation for 1-Bromo-4-(trimethylsiloxy)benzene, please contact our sales team through the website or by phone. Our specialists are ready to assist with your requirements.
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