1-Bromo-4-(difluoromethyl)-2-fluorobenzene
1-Bromo-4-(difluoromethyl)-2-fluorobenzene (CAS 1214386-70-5, C7H4BrF3) is a specialised aryl building block supplied by Tech Serve Solutions. With a molecular weight of 225.01, this compound is valuable in organic synthesis, particularly for introducing fluorinated motifs. Its structure makes it a versatile intermediate for the development of new pharmaceuticals and agrochemicals, fitting into C9 to C12 chemical synthesis pathways.

Fluorinated Intermediate Synthesis
This compound serves as a key intermediate for incorporating difluoromethyl and fluoroaryl groups into complex organic molecules. It is instrumental in the synthesis of novel compounds with potential applications in medicinal chemistry and materials science.
Pharmaceutical Research
1-Bromo-4-(difluoromethyl)-2-fluorobenzene is utilised in the research and development of new pharmaceutical agents. The presence of fluorine atoms can significantly influence a drug candidate's metabolic stability, lipophilicity, and binding affinity.
Agrochemical Development
The unique structural features of this chemical make it a useful building block for creating novel agrochemicals. Researchers can leverage its properties to design more effective and selective pesticides or herbicides.
Advanced Organic Synthesis
As a halogenated and fluorinated aromatic compound, it offers distinct reactivity for various coupling reactions and functional group transformations, supporting complex synthetic strategies.
| Molecular weight | 225.01 |
|---|---|
| Empirical formula | C7H4BrF3 |
| Assay | 97% |
| Density | 1.679 g/mL at 25 °C |
| Refractive index | n20/D 1.499 |
| Storage temperature | 2-8°C |

Hazard statements
- H302Harmful if swallowed
- H319Causes serious eye irritation
Precautionary statements
- P305IF IN EYES
| Flash point | 90 °C / 194 °F |
|---|---|
| Transport (UN / ADR) | NA 1993 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36-52 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-Bromo-4-(difluoromethyl)-2-fluorobenzene used for?
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This compound is primarily used as a building block in organic synthesis, particularly for introducing difluoromethyl and fluoroaryl moieties into more complex molecules. It finds applications in pharmaceutical research, agrochemical development, and advanced chemical synthesis.
What is the CAS number and formula for 1-Bromo-4-(difluoromethyl)-2-fluorobenzene?
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The CAS number is 1214386-70-5 and the empirical formula is C7H4BrF3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1-Bromo-4-(difluoromethyl)-2-fluorobenzene with an assay of 97%. TSS does not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
What are the safety and handling recommendations for this chemical?
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This compound is classified with GHS07 symbol and a Warning signal word. It has hazard statements H302 (Harmful if swallowed) and H319 (Causes serious eye irritation). Handle with appropriate personal protective equipment, ensure good ventilation, and follow precautionary statement P305 + P351 + P338 (If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing).
Is this chemical suitable for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, and 1-Bromo-4-(difluoromethyl)-2-fluorobenzene can be shipped internationally, adhering to all necessary regulations.
How can I request a sample or quote for this product?
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To request a sample or a quote, please contact our sales team through the website or by phone, providing the product name and CAS number (1214386-70-5).
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