1-Acetyl-3-methylpiperidine
1-Acetyl-3-methylpiperidine (CAS: 4593-16-2) is a heterocyclic organic compound with the molecular formula C8H15NO and a molecular weight of 141.21 g/mol. This piperidine derivative serves as a valuable reactant in organic synthesis. It is particularly employed in regioselective amidyl radical cyclization and the regioselective oxidation of cyclic amino compounds, making it a useful building block for complex molecular architectures.
- IUPAC
- 1-(3-Methyl-1-piperidinyl)-ethanone,1-Acetyl-3-pipecoline
- Synonyms
- 1-(3-Methyl-1-piperidinyl)-ethanone1-Acetyl-3-pipecoline

Regioselective Amidyl Radical Cyclization
1-Acetyl-3-methylpiperidine functions as a key reactant in regioselective amidyl radical cyclization reactions, enabling the formation of specific cyclic structures.
Regioselective Oxidation of Cyclic Amino Compounds
This compound is utilized in the regioselective oxidation of cyclic amino compounds, contributing to the controlled synthesis of oxidised derivatives.
Organic Synthesis Building Block
As a heterocyclic building block, 1-Acetyl-3-methylpiperidine offers a versatile scaffold for constructing more complex organic molecules in various research and development settings.
| Molecular weight | 141.21 |
|---|---|
| Empirical formula | C8H15NO |
| Assay | 99% |
| Boiling point | 239 °C(lit.) |
| Density | 0.974 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.476(lit.) |
| Application | Reactant for: Regioselective amidyl radical cyclization1 Regioselective oxidation of cyclic amino compounds2 |
| Melting point | −15 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 107 °C / 224.6 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-Acetyl-3-methylpiperidine used for?
+
1-Acetyl-3-methylpiperidine is used as a reactant in regioselective amidyl radical cyclization and the regioselective oxidation of cyclic amino compounds. It is also a useful heterocyclic building block in organic synthesis.
What is the CAS number and molecular formula for 1-Acetyl-3-methylpiperidine?
+
The CAS number is 4593-16-2, and the molecular formula is C8H15NO.
What grade and purity does Tech Serve Solutions supply for 1-Acetyl-3-methylpiperidine?
+
Tech Serve Solutions supplies 1-Acetyl-3-methylpiperidine with an assay of 99%. This product is supplied for research and development purposes and is not represented as USP, BP, or EP grade.
What are the main hazards associated with 1-Acetyl-3-methylpiperidine?
+
1-Acetyl-3-methylpiperidine is classified with the GHS07 symbol and carries a Warning signal word. It causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including eyeshields and gloves, should be used when handling.
How is 1-Acetyl-3-methylpiperidine packed and shipped?
+
1-Acetyl-3-methylpiperidine is carefully packed to ensure safe transit and is available for export worldwide by Tech Serve Solutions.
How can I request a quote or sample for 1-Acetyl-3-methylpiperidine?
+
To request a quote or sample of 1-Acetyl-3-methylpiperidine, please contact our sales team through the TSS website.
▶ Related products

1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis

1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis