1-Acetyl-4-(4-hydroxyphenyl)piperazine
1-Acetyl-4-(4-hydroxyphenyl)piperazine (CAS 67914-60-7) is a heterocyclic organic compound with the molecular formula C12H16N2O2 and a molecular weight of 220.27 g/mol. It serves as a valuable building block in chemical synthesis, particularly within the realm of heterocyclic chemistry. This compound is recognised for its utility in the development of novel molecules and research applications.
- IUPAC
- Piperazine, 1-acetyl-4-(4-hydroxyphenyl)- (9CI) 1-Acetyl-4-(4-hydroxyphenyl)piperazine 1-Acetyl-4-(p-hydroxyphenyl)piperazine 1-[4-(4-Hydroxyphenyl)piperazin-1-yl]ethanone 4-(4-Acetylpiperazin-1-yl)phenol 4-(4-Acetylpiperazino)phenol T 1141
- Synonyms
- Piperazine, 1-acetyl-4-(4-hydroxyphenyl)- (9CI)1-Acetyl-4-(4-hydroxyphenyl)piperazine1-Acetyl-4-(p-hydroxyphenyl)piperazine1-[4-(4-Hydroxyphenyl)piperazin-1-yl]ethanone4-(4-Acetylpiperazin-1-yl)phenol4-(4-Acetylpiperazino)phenolT 1141

Chemical Synthesis Intermediate
This compound functions as a key intermediate in organic synthesis. Its structure allows for further functionalization and incorporation into more complex molecular architectures, supporting the development of new chemical entities.
Research and Development
1-Acetyl-4-(4-hydroxyphenyl)piperazine is utilised in laboratory settings for research and development purposes, aiding chemists in exploring new synthetic pathways and novel compound discovery.
Building Block for Heterocycles
As a piperazine derivative, it is particularly useful for constructing molecules containing the piperazine moiety, a common structural feature in pharmaceuticals and other bioactive compounds.
| Molecular weight | 220.27 |
|---|---|
| Empirical formula | C12H16N2O2 |
| Assay | 98% |
| Melting point | 180-185 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-Acetyl-4-(4-hydroxyphenyl)piperazine used for?
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1-Acetyl-4-(4-hydroxyphenyl)piperazine is primarily used as a building block in chemical synthesis and for research and development purposes.
What is the CAS number and formula for this compound?
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The CAS number is 67914-60-7, and the empirical formula is C12H16N2O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1-Acetyl-4-(4-hydroxyphenyl)piperazine with an assay of 98%. This product is supplied for research and technical use; TSS does not represent it as USP, BP, or EP grade.
How should 1-Acetyl-4-(4-hydroxyphenyl)piperazine be handled?
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Handle with appropriate personal protective equipment, including a dust mask (type N95 US recommended), eyeshields, and gloves. Avoid breathing dust. Ensure adequate ventilation. This compound is classified as a Warning, with hazards including skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335).
Is this compound available for export?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 1-Acetyl-4-(4-hydroxyphenyl)piperazine.
How can I request a sample or quote?
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To request a sample or a quotation for 1-Acetyl-4-(4-hydroxyphenyl)piperazine, please contact our sales team through the website or via the provided contact details.
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