1-Acetyl-3-indolecarboxaldehyde
1-Acetyl-3-indolecarboxaldehyde (CAS: 22948-94-3, C11H9NO2, MW: 187.19) is a versatile indole derivative and aldehyde. It functions as a key building block in organic synthesis. Its applications span the creation of antiviral agents targeting Dengue virus protease, antimicrobial compounds, potential tuberculostatic agents, and probes for live cell imaging. This compound is supplied by TSS for research and chemical synthesis purposes.
- IUPAC
- N-Acetylindol-3-carboxaldehyde,NSC 61289
Antiviral Agents Synthesis
Used as a reactant in the synthesis of alpha-ketoamides that exhibit antiviral activity against Dengue virus protease in cell cultures.
Antimicrobial Agents
Serves as a reactant in the preparation of homoallylic amines, which are investigated for their potential as antimicrobial agents.
Tuberculostatic Agents
Acts as a reactant in the preparation of pyrrole-based hydrazones, explored for their potential as tuberculostatic compounds.
RNA-Specific Imaging Probes
Utilised as a reactant in the synthesis of RNA-specific probes, such as E36, E144, and F22, designed for live cell imaging.
Sensitizing Agents
Employed in the synthesis of substituted indolyl-methylene quinuclidinone and quinuclidinol derivatives with potent thermal sensitizing properties.
| Molecular weight | 187.19 |
|---|---|
| Empirical formula | C11H9NO2 |
| Assay | 98% |
| Application | Reactant for synthesis of α-ketoamides as inhibitors of Dengue virus protease with antiviral activity in cell-culture1Reactant for preparation of homoallylic amines as antimicrobial agents2Reactant for preparation of pyrrole-based hydrazones as potential tuberculostatics3Reactant for synthesis of neoechinulin A and derivatives4Reactant for synthesis of substituted (Z)-2-(N-benzylindol-3-ylmethylene)quinuclidin-3-one and (Z)-(±)-2-(N-benzylindol-3-ylmethylene)quinuclidin-3-ol derivatives as potent thermal sensitizing agents5Reactant for preparation of RNA-specific live cell imaging probes E36, E144 and F226 |
| Melting point | 165 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-Acetyl-3-indolecarboxaldehyde used for?
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1-Acetyl-3-indolecarboxaldehyde is primarily used as a reactant and building block in organic synthesis. Its applications include the synthesis of antiviral agents, antimicrobial compounds, potential tuberculostatics, and RNA-specific live cell imaging probes.
What is the CAS number and formula for 1-Acetyl-3-indolecarboxaldehyde?
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The CAS number is 22948-94-3 and the empirical formula is C11H9NO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1-Acetyl-3-indolecarboxaldehyde with an assay of 98%. This product is intended for research and chemical synthesis and is not represented as USP, BP, EP, or other pharmacopoeia grades.
How should 1-Acetyl-3-indolecarboxaldehyde be handled safely?
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This compound is a Warning substance with hazards including skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Handle with appropriate personal protective equipment, including a dust mask (N95), eyeshields, and gloves. Ensure adequate ventilation.
How is this chemical packed and shipped?
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1-Acetyl-3-indolecarboxaldehyde is carefully packed according to industry standards for safe transportation and export globally by Tech Serve Solutions.
How can I request a quote or sample?
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To request a quote or sample of 1-Acetyl-3-indolecarboxaldehyde, please contact our sales team through the website or by calling our direct line.
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