(R)-4-Benzyl-3-chloroacetyl-2-oxazolidinone
(R)-4-Benzyl-3-chloroacetyl-2-oxazolidinone (CAS: 184714-56-5) is a chiral auxiliary with the molecular formula C12H12ClNO3 and a molecular weight of 253.68 g/mol. Supplied at 97% purity, this compound is valuable in organic synthesis, particularly for asymmetric reactions. Its oxazolidinone structure facilitates the stereoselective introduction of substituents, making it a key building block in complex molecule construction. Available from TSS for research and development purposes.
- IUPAC
- (N-Chloroacetyl)-(4R)-benzyl-2-oxazolidinone

Chiral Auxiliary in Asymmetric Synthesis
This oxazolidinone derivative serves as a crucial chiral auxiliary. It enables the stereocontrolled formation of new chiral centres during chemical synthesis, which is vital for producing enantiomerically pure compounds.
Building Block for Complex Molecules
The compound is utilized as a versatile building block in the synthesis of complex organic molecules. Its functional groups allow for various synthetic transformations, aiding in the construction of pharmaceutical intermediates and fine chemicals.
Stereoselective Alkylation and Acylation
It is employed in stereoselective alkylation and acylation reactions. The chiral nature of the auxiliary directs the incoming electrophile to a specific face of the molecule, ensuring high diastereoselectivity.
| Molecular weight | 253.68 |
|---|---|
| Empirical formula | C12H12ClNO3 |
| Assay | 97% |
| Optical activity | [α]20/D −70°, c = 1 in chloroform |
| Melting point | 78-82 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-4-Benzyl-3-chloroacetyl-2-oxazolidinone used for?
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(R)-4-Benzyl-3-chloroacetyl-2-oxazolidinone is primarily used as a chiral auxiliary in asymmetric synthesis and as a building block for constructing complex organic molecules, facilitating stereoselective reactions like alkylation and acylation.
What are the CAS number and formula for this compound?
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The CAS number is 184714-56-5, and the empirical formula (Hill notation) is C12H12ClNO3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound with an assay of 97%. We do not represent this product as USP, EP, or BP grade.
How should (R)-4-Benzyl-3-chloroacetyl-2-oxazolidinone be handled?
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Handle with appropriate personal protective equipment, including a dust mask (type N95 US recommended), eyeshields, and gloves. Avoid breathing dust and ensure adequate ventilation. This compound is a Warning irritant to skin, eyes, and respiratory tract.
How is this chemical packed, shipped, and exported?
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TSS can export this chemical globally. Packaging is handled according to international shipping regulations to ensure product integrity and safety during transit.
How can I request a quote or sample?
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To request a quote or sample, please contact our sales team via the website or direct email, providing the product name and CAS number.
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