1-Naphthyl isothiocyanate
1-Naphthyl isothiocyanate (CAS: 551-06-4; C10H7NCS) is a chemical compound with a molecular weight of 185.24 g/mol. It is primarily utilised as an analytical reagent, particularly for derivatisation in chromatography, and as a building block in chemical synthesis. Its reactivity makes it valuable in various organic transformations and in the development of new chemical entities.
Analytical Derivatisation Reagent
1-Naphthyl isothiocyanate is employed as a derivatising agent in analytical chemistry, notably for the analysis of amines and amino acids. It reacts to form stable derivatives that exhibit enhanced detectability, particularly in HPLC with UV-Vis detection.
Organic Synthesis Building Block
This compound serves as a versatile building block in organic synthesis. Its isothiocyanate functional group readily participates in addition reactions, allowing for the construction of more complex molecules for research and development purposes.
Chromatographic Analysis
As a derivatisation reagent, it is used in chromatographic techniques like HPLC to improve the separation and detection of analytes by increasing their detectability and stability.
| Molecular weight | 185.24 |
|---|---|
| Linear formula | C10H7NCS |
| Assay | 95% |
| Melting point | 55.5-57 °C(lit.) |
Hazard statements
- H301Toxic if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H334May cause allergy or asthma symptoms if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P305IF IN EYES
- P342
| Protective equipment | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 20/21-25-36/37/38-42 |
| Safety statements (S) | 22-26-36/37-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-Naphthyl isothiocyanate used for?
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1-Naphthyl isothiocyanate is used as an analytical reagent for derivatisation in chromatography, as a building block in chemical synthesis, and for developing new chemical entities.
What is the CAS number and formula for 1-Naphthyl isothiocyanate?
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The CAS number is 551-06-4 and the chemical formula is C10H7NCS.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1-Naphthyl isothiocyanate with an assay of 95%. We do not represent this product as USP, BP, or EP grade.
What are the primary safety concerns with 1-Naphthyl isothiocyanate?
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1-Naphthyl isothiocyanate is classified as dangerous. It is toxic if swallowed, toxic in contact with skin, toxic if inhaled, causes skin irritation, causes serious eye irritation, may cause respiratory irritation, and may cause allergy or asthma symptoms or breathing difficulties if inhaled. Appropriate personal protective equipment, including eyeshields, face shields, gloves, and P2 respirator cartridges, must be used.
How is 1-Naphthyl isothiocyanate packed, shipped, and exported?
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1-Naphthyl isothiocyanate is packed and shipped in compliance with international regulations for hazardous materials. As a global supplier, Tech Serve Solutions has extensive experience in exporting such chemicals worldwide.
How can I request a sample or quote for 1-Naphthyl isothiocyanate?
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To request a sample or a quote, please contact our sales department through the 'Contact Us' section of our website or by calling our offices. Please provide your specific requirements and shipping details.
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