1-Naphthyl trifluoromethanesulfonate
1-Naphthyl trifluoromethanesulfonate (CAS 99747-74-7), with the molecular formula CF3SO3C10H7 and a molecular weight of 276.23 g/mol, is an organic triflate. This compound serves as a valuable building block in organic synthesis, particularly for introducing the 1-naphthyloxy group. It is utilised in the preparation of complex molecules and fine chemical intermediates, leveraging the reactivity of the triflate leaving group.
- IUPAC
- 1-Naphthyl triflate

Organic Synthesis Intermediate
1-Naphthyl trifluoromethanesulfonate acts as a key intermediate in the synthesis of various organic compounds. Its triflate group makes it an excellent electrophile for nucleophilic substitution reactions.
Building Block for Complex Molecules
This compound is employed as a fundamental building block in the construction of more complex molecular architectures. It is particularly useful in pharmaceutical research and development for creating novel drug candidates.
Preparation of Specialty Chemicals
It finds application in the chemical industry for the preparation of specialty chemicals and fine chemical intermediates, where precise functional group introduction is required.
| Molecular weight | 276.23 |
|---|---|
| Linear formula | CF3SO3C10H7 |
| Assay | 97% |
| Boiling point | 97-98 °C/0.3 mmHg(lit.) |
| Density | 1.405 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.52(lit.) |

Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Transport (UN / ADR) | UN 3265 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 23-26-27-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-Naphthyl trifluoromethanesulfonate used for?
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1-Naphthyl trifluoromethanesulfonate is primarily used as a building block in organic synthesis for the preparation of complex molecules and fine chemical intermediates.
What is the CAS number and molecular formula for 1-Naphthyl trifluoromethanesulfonate?
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The CAS number for 1-Naphthyl trifluoromethanesulfonate is 99747-74-7, and its molecular formula is CF3SO3C10H7.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1-Naphthyl trifluoromethanesulfonate with an assay of 97%. We do not represent this product as USP, BP, or EP grade.
How should 1-Naphthyl trifluoromethanesulfonate be handled?
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1-Naphthyl trifluoromethanesulfonate is a corrosive substance (H314). Handle with extreme care, using appropriate personal protective equipment including face shields, goggles, gloves, and respiratory protection (full-face respirator or multi-purpose combination respirator cartridge, type ABEK filter). Ensure adequate ventilation.
How is 1-Naphthyl trifluoromethanesulfonate packed and shipped?
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1-Naphthyl trifluoromethanesulfonate is shipped as UN 3265, Class 8, Packing Group II, indicating it is a corrosive liquid, acidic, organic, N.O.S. Packaging adheres to strict international regulations for hazardous materials.
How can I request a sample or quote for 1-Naphthyl trifluoromethanesulfonate?
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To request a sample or quote for 1-Naphthyl trifluoromethanesulfonate, please contact our sales team through the website or by phone, providing your specific requirements.
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