1-Naphthoyl chloride
1-Naphthoyl chloride (CAS 879-18-5), with the molecular formula C arr10 arr7COCl and a molecular weight of 190.63 g/mol, is a significant organic compound. It serves as a valuable reagent in various chemical syntheses and analytical applications. Its utility spans derivatization for chromatographic analysis and participation in reactions like the Arndt-Eistert synthesis. This acid halide is supplied by Tech Serve Solutions with an assay of 97%.
Derivatization Reagent
1-Naphthoyl chloride is employed as a derivatization reagent in analytical chemistry. It has been utilised in the analysis of short-chained dodecyl alcohol ethoxylates and dodecyl alcohol, often in conjunction with solid-phase extraction and dispersive liquid-liquid microextraction techniques.
Fluorescent Labeling
This compound functions as a fluorescent labelling reagent. It is useful in the precise determination of toxins, such as T-2 and HT-2 toxins, when employing high-performance liquid chromatography (HPLC) with fluorescence detection.
Arndt-Eistert Synthesis
1-Naphthoyl chloride finds application in organic synthesis, specifically within the Arndt-Eistert synthesis methodology. This reaction is typically performed in the presence of reagents like trimethylsilyldiazomethane.
Preparation of Indole Derivatives
The chemical is used in the preparation of specific organic compounds, such as 2-ethyl-1-pentyl-3-(1-naphthoyl)indole. This demonstrates its utility in the synthesis of complex heterocyclic structures.
| Molecular weight | 190.63 |
|---|---|
| Linear formula | C10H7COCl |
| Assay | 97% |
| Boiling point | 190 °C/35 mmHg(lit.) |
| Density | 1.265 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.652(lit.) |
| Application | 1-Naphthoyl chloride has been used:• as derivatization reagent in analysis of short-chained dodecyl alcohol ethoxylates and dodecyl alcohol by solid-phase extraction combined with dispersive liquid-liquid microextraction method1• as fluorescent labeling reagent in determination of T-2 and HT-2 toxins by HPLC with fluorescence detection2• in Arndt-Eistert synthesis in the presence of trimethylsilyldiazomethane3• in preparation of 2-ethyl-1-pentyl-3-(1-naphthoyl)indole4 |
| Melting point | 16-19 °C(lit.) |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | >110 °C / >230 °F |
| Transport (UN / ADR) | UN 3265 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34-37 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What are the primary uses of 1-Naphthoyl chloride?
+
1-Naphthoyl chloride is primarily used as a derivatization reagent in analytical methods, as a fluorescent labelling agent, and in organic synthesis, including the Arndt-Eistert synthesis and the preparation of indole derivatives.
What is the CAS number and molecular formula for 1-Naphthoyl chloride?
+
The CAS number for 1-Naphthoyl chloride is 879-18-5, and its linear molecular formula is C arr10 arr7COCl.
What grade and purity does Tech Serve Solutions supply for 1-Naphthoyl chloride?
+
Tech Serve Solutions supplies 1-Naphthoyl chloride with an assay of 97%. This product is intended for laboratory and research use. TSS does not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should 1-Naphthoyl chloride be handled safely?
+
1-Naphthoyl chloride is a corrosive substance (H314) that causes severe skin burns and eye damage. Handling requires stringent safety precautions, including the use of personal protective equipment such as gloves, goggles, and a faceshield. Work should be conducted in a well-ventilated area, and appropriate respiratory protection (e.g., ABEK filter) should be used. Immediate medical attention is necessary in case of contact or exposure.
Is 1-Naphthoyl chloride shipped internationally?
+
Yes, Tech Serve Solutions, a specialist global supplier and exporter since 1998, can pack and export 1-Naphthoyl chloride to qualified international customers.
How can I request a quote or sample for 1-Naphthoyl chloride?
+
To request a quote or a sample of 1-Naphthoyl chloride, please contact our sales department through the provided channels on the Tech Serve Solutions website.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis