1-(5-Bromo-2-hydroxyphenyl)-3-(diethylamino)-2-propen-1-one
1-(5-Bromo-2-hydroxyphenyl)-3-(diethylamino)-2-propen-1-one (CAS 213690-00-7; C13H16BrNO2; molar mass 298.18 g/mol) is a brominated, hydroxy-substituted aryl enaminone supplied by Tech Serve Solutions as a research-grade organic building block at 97% assay. A crystalline solid melting at 73-77 degC, this push-pull enaminone bears reactive ketone, phenol and bromoaryl handles, making it a versatile intermediate for heterocyclic synthesis and medicinal-chemistry exploration.
- Synonyms
- 1-(5-Bromo-2-hydroxyphenyl)-3-(diethylamino)-2-propen-1-one1-(5-Bromo-2-hydroxyphenyl)-3-(diethylamino)prop-2-en-1-one(E)-1-(5-bromo-2-hydroxyphenyl)-3-(diethylamino)prop-2-en-1-one3-(diethylamino)-1-(5-bromo-2-hydroxyphenyl)-2-propen-1-oneCAS 213690-00-7MFCD03424558
Heterocyclic synthesis building block
The diethylamino enaminone motif is a recognised three-carbon synthon for constructing nitrogen and oxygen heterocycles such as chromones, pyrazoles and pyrimidines. The dimethylamino/diethylamino group acts as a leaving unit during cyclocondensation, enabling ring closure with binucleophiles.
Fine-chemical and pharmaceutical intermediate
As a multifunctional aryl ketone carrying a phenol and an aryl bromide, it serves as an intermediate in the preparation of more elaborate molecules for medicinal-chemistry and discovery programmes. It is offered for research and development use, not for therapeutic application.
Cross-coupling substrate
The aromatic carbon-bromine bond provides a handle for palladium-catalysed transformations such as Suzuki, Heck and related cross-coupling reactions, allowing further functionalisation of the aromatic ring during synthetic route development.
Laboratory reagent for method development
Supplied at 97% purity, the compound suits exploratory and small-scale synthetic chemistry, reaction screening and structure-activity studies where a defined, characterised enaminone scaffold is required.
| Molecular weight | 298.18 |
|---|---|
| Linear formula | BrC6H3(OH)COCH=CHN(C2H5)2 |
| Assay | 97% |
| Melting point | 73-77 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-(5-Bromo-2-hydroxyphenyl)-3-(diethylamino)-2-propen-1-one used for?
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It is used as an organic building block and synthetic intermediate. The diethylamino enaminone group is a versatile synthon for building heterocycles (such as chromones, pyrazoles and pyrimidines), while the aryl bromide and phenol functionalities allow further derivatisation. It is supplied for research, development and laboratory use.
What is the CAS number and molecular formula of 1-(5-Bromo-2-hydroxyphenyl)-3-(diethylamino)-2-propen-1-one?
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Its CAS number is 213690-00-7 and its molecular formula is C13H16BrNO2 (linear formula BrC6H3(OH)COCH=CHN(C2H5)2), with a molecular weight of 298.18 g/mol. The MDL number is MFCD03424558 and it melts at 73-77 degC.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product at a minimum assay of 97% as a research and laboratory-grade building block. It is offered as a technical/research-grade material; we do not represent it as USP, BP or EP pharmacopoeial grade. A certificate of analysis can be provided on request.
What are the safety and handling requirements for this compound?
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It is classified under GHS with signal word Warning (pictogram GHS07). The hazard statements are H315 (causes skin irritation), H319 (causes serious eye irritation) and H335 (may cause respiratory irritation). Handle with gloves, eye protection and an N95-type dust mask, avoid dust formation, and follow precautionary advice P261 and P305+P351+P338. It carries German Water Hazard Class WGK 3 (highly hazardous to water), so prevent release to the environment. Always consult the Safety Data Sheet before use.
How is 1-(5-Bromo-2-hydroxyphenyl)-3-(diethylamino)-2-propen-1-one packed, shipped and exported?
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The product is packed in tightly sealed, appropriately labelled containers sized to the order, from gram quantities to bulk. As a specialist exporter, Tech Serve Solutions arranges compliant international documentation and dispatch, with full identity and analytical paperwork accompanying each consignment.
How do I request a sample or quote?
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Contact Tech Serve Solutions with your required quantity, packaging and destination, quoting CAS 213690-00-7. We will respond with availability, lead time and a formal quotation, and can supply a certificate of analysis and Safety Data Sheet to support your evaluation.
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