1-(5-Bromo-3-fluoropyridin-2-yl)ethanone
1-(5-Bromo-3-fluoropyridin-2-yl)ethanone (CAS 1160936-52-6) is a halogenated pyridine building block with the molecular formula C7H5BrFNO and a molar mass of 218.02 g/mol. It combines an acetyl group with a reactive aryl bromide and a ring fluorine on a single pyridine scaffold, making it a versatile intermediate for medicinal chemistry and fine-chemical synthesis. Tech Serve Solutions supplies and exports this fluorinated heterocyclic reagent to research and process-development laboratories worldwide.
- Synonyms
- 1-(5-Bromo-3-fluoropyridin-2-yl)ethanone1-(5-bromo-3-fluoro-2-pyridinyl)ethanone5-bromo-3-fluoro-2-acetylpyridine2-acetyl-5-bromo-3-fluoropyridineCAS 1160936-52-6C7H5BrFNO
Pharmaceutical and agrochemical intermediate
Serves as a multifunctional building block in the synthesis of pharmaceutical candidates and agrochemicals. The fluorinated pyridine core is a common motif used to modulate metabolic stability and binding in discovery programmes.
Cross-coupling substrate
The aryl bromide provides a selective handle for palladium-catalysed cross-coupling reactions such as Suzuki, Stille and Buchwald-Hartwig chemistry, enabling rapid elaboration of the pyridine ring.
Ketone-based derivatisation
The acetyl (methyl ketone) group offers a reactive site for condensations, reductive amination, enolate chemistry and heterocycle formation, supporting the construction of more complex scaffolds.
Fluorinated scaffold for structure-activity studies
As a fluorinated heterocyclic building block, it is used to introduce a ring fluorine in medicinal-chemistry analogue series and structure-activity relationship investigations.
Research and laboratory reagent
Used in academic and industrial laboratories as a reference intermediate and reagent for method development and small-scale synthetic route exploration.
| Molecular weight | 218.02 |
|---|---|
| Empirical formula | C7H5BrFNO |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-(5-Bromo-3-fluoropyridin-2-yl)ethanone used for?
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It is used as a fluorinated pyridine building block in chemical synthesis. The reactive aryl bromide and methyl ketone make it valuable for cross-coupling reactions and ketone derivatisation in pharmaceutical, agrochemical and fine-chemical research and development.
What is the CAS number and molecular formula of 1-(5-Bromo-3-fluoropyridin-2-yl)ethanone?
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The CAS number is 1160936-52-6 and the molecular formula is C7H5BrFNO, with a molecular weight of 218.02 g/mol. It is a fluorinated heterocyclic building block belonging to the pyridine class.
What grade and purity does Tech Serve Solutions supply?
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We supply 1-(5-Bromo-3-fluoropyridin-2-yl)ethanone as a research and laboratory reagent grade material, with the assay confirmed for each batch on the accompanying Certificate of Analysis. We do not represent this product as USP, BP or EP pharmacopoeia grade; specific purity requirements can be discussed at the time of enquiry.
How should 1-(5-Bromo-3-fluoropyridin-2-yl)ethanone be handled and stored?
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Handle in accordance with good laboratory practice: use appropriate personal protective equipment, avoid contact with skin and eyes, and work in a well-ventilated area or fume hood. Store tightly closed in a cool, dry place away from incompatible materials. Always consult the current Safety Data Sheet supplied with the product before use.
How is 1-(5-Bromo-3-fluoropyridin-2-yl)ethanone packed, shipped and exported?
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The product is packed in suitable laboratory and bulk containers with full labelling and documentation, and exported worldwide. Pack sizes, packaging specifications and shipping arrangements are confirmed at the time of order to suit your destination and regulatory requirements.
How do I request a sample or quote?
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Contact Tech Serve Solutions with your required quantity, purity specification and destination, quoting CAS 1160936-52-6. Our team will respond with availability, lead time and a quotation, and arrange samples where appropriate.
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