1-(3-Bromopropyl)-2,2,5,5-tetramethyl-1-aza-2,5-disilacyclopentane
1-(3-Bromopropyl)-2,2,5,5-tetramethyl-1-aza-2,5-disilacyclopentane (CAS 95091-93-3; C9H22BrNSi2; molar mass 280.35 g/mol) is an organosilicon building block supplied at 97% assay. It is a clear, flammable liquid that pairs a reactive 3-bromopropyl handle with a cyclic disilazane (azasilolidine) ring acting as a masked primary-amine group. It is used in organic synthesis to install a protected 3-aminopropyl unit, with the amine released on aqueous work-up.
- Synonyms
- 1-(3-Bromopropyl)-2,2,5,5-tetramethyl-1-aza-2,5-disilacyclopentane2,2,5,5-Tetramethyl-1-(3-bromopropyl)-1-aza-2,5-disilacyclopentane1-(3-Bromopropyl)-2,2,5,5-tetramethyl-1-aza-2,5-disilolidineCAS 95091-93-3C9H22BrNSi2MFCD00274342
Masked aminopropyl building block
The 2,2,5,5-tetramethyl-1-aza-2,5-disilacyclopentane (Stabase-type) ring serves as a protected primary amine. This compound lets chemists introduce a 3-aminopropyl group, with the free amine revealed by mild aqueous or acidic hydrolysis of the disilazane.
Alkylating reagent in C–C and C–heteroatom bond formation
The primary alkyl bromide on the propyl chain undergoes nucleophilic substitution and metalation, allowing the protected aminopropyl fragment to be coupled onto nucleophiles, enolates or organometallic partners during multi-step synthesis.
Halogenated heterocyclic intermediate
Classed as a nitrogen-containing, halogenated heterocyclic building block, it is employed as an intermediate in the preparation of more complex target molecules where a terminal amine must be carried through reactive steps in masked form.
Research and laboratory-scale synthesis
It is used as a reagent for exploratory and method-development chemistry in research, discovery and process laboratories that require a bifunctional amine-protected electrophile.
| Molecular weight | 280.35 |
|---|---|
| Empirical formula | C9H22BrNSi2 |
| Assay | 97% |
| Boiling point | 80 °C/0.5 mmHg(lit.) |
| Density | 1.126 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.484(lit.) |
Hazard statements
- H226Flammable liquid and vapour
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 35 °C / 95 °F |
| Transport (UN / ADR) | UN 1993C 3 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Risk statements (R) | 10 |
| Safety statements (S) | 16 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-(3-Bromopropyl)-2,2,5,5-tetramethyl-1-aza-2,5-disilacyclopentane used for?
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It is used in organic synthesis as a bifunctional building block: the cyclic disilazane ring acts as a masked primary amine, while the 3-bromopropyl group provides a reactive alkyl-halide handle. This allows a protected 3-aminopropyl unit to be installed by alkylation or metalation, with the amine freed on aqueous work-up.
What is the CAS number and molecular formula of 1-(3-Bromopropyl)-2,2,5,5-tetramethyl-1-aza-2,5-disilacyclopentane?
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The CAS number is 95091-93-3 and the empirical (Hill) formula is C9H22BrNSi2, with a molecular weight of 280.35 g/mol. The MDL number is MFCD00274342 and the PubChem Substance ID is 24869593.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product at a typical assay of 97% as a research and laboratory reagent grade. We do not represent it as USP, BP or EP pharmacopoeial grade. A certificate of analysis can be provided with each batch on request.
What are the safety and handling requirements?
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It is classified under GHS02 with the signal word Warning and hazard statement H226 (flammable liquid and vapour); the flash point is about 35 °C. Keep away from heat, sparks and open flame, use under inert and well-ventilated conditions, and wear eye and face protection, gloves and suitable respiratory protection. It carries water-hazard class WGK 3 (Germany), so prevent release to the environment. Always consult the SDS before use.
How is it packed, shipped and exported?
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As a flammable liquid it is classified for transport as UN 1993, Class 3, Packing Group III, and is supplied in appropriately sealed, compatible containers with full labelling and documentation. Tech Serve Solutions exports worldwide in compliance with applicable dangerous-goods regulations, with pack sizes arranged to suit your requirement.
How do I request a sample or quote?
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Contact Tech Serve Solutions with the product name, CAS number 95091-93-3, your required quantity and destination country, and we will confirm availability, packing, lead time and export terms. Samples may be available subject to dangerous-goods shipping requirements.
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