1-(3-Bromo-1-propynyl)naphthalene
1-(3-Bromo-1-propynyl)naphthalene (CAS 352035-98-4; C13H9Br; molar mass 245.11 g/mol) is a low-melting brominated propynyl naphthalene supplied at 97% assay as a research-grade synthetic reagent. It serves principally as a reagent for the protection of alcohols, installing a 1-naphthylpropargyl ether that is later cleaved oxidatively with DDQ. Tech Serve Solutions supplies and exports this hydroxyl-protecting reagent to laboratory, fine-chemical and research customers worldwide.
- Synonyms
- 1-(3-Bromo-1-propynyl)naphthalene1-(3-Bromoprop-1-ynyl)naphthalene1-(3-Bromo-1-propyn-1-yl)naphthalene3-(1-Naphthyl)-2-propynyl bromide1-naphthylpropargyl bromide reagentCAS 352035-98-4
Hydroxyl protection as a naphthylpropargyl ether
Used to convert alcohols into the corresponding 1-naphthylpropargyl ether, providing a stable protecting group during multistep synthesis. The protected hydroxyl can later be liberated under controlled oxidative conditions.
DDQ-cleavable protecting group
The naphthylpropargyl ether installed by this reagent is removed oxidatively using DDQ, offering an orthogonal deprotection option that complements other common alcohol-protecting strategies.
Building block for organic synthesis
As a propargyl bromide bearing a naphthalene unit, it can act as an alkylating and propargylating reagent in carbon-carbon and carbon-heteroatom bond-forming reactions where a naphthylpropynyl fragment is required.
Research and method-development reagent
Employed in academic and industrial laboratories for synthetic methodology, protecting-group studies and the preparation of naphthalene-substituted intermediates at research scale.
| Molecular weight | 245.11 |
|---|---|
| Empirical formula | C13H9Br |
| Assay | 97% |
| Application | Reagent for the protection of alcohols in the form of a 1-naphthylpropargyl ether that can be cleaved with DDQ.1 |
| Melting point | 43-47 °C |
Hazard statements
- H315Causes skin irritation
- H318Causes serious eye damage
- H335May cause respiratory irritation
- H400Very toxic to aquatic life
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P273Avoid release to the environment
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Flash point | >110 °C / >230 °F |
| Transport (UN / ADR) | UN 3082 9 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi,N |
| Risk statements (R) | 37/38-41-50 |
| Safety statements (S) | 26-39-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-(3-Bromo-1-propynyl)naphthalene used for?
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It is primarily used as a reagent for the protection of alcohols, converting a hydroxyl group into a 1-naphthylpropargyl ether that can subsequently be cleaved with DDQ. It also serves as a naphthylpropargyl building block in organic synthesis.
What is the CAS number and molecular formula of 1-(3-Bromo-1-propynyl)naphthalene?
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The CAS number is 352035-98-4 and the molecular formula is C13H9Br, with a molecular weight of 245.11 g/mol. It is a low-melting solid with a melting point of approximately 43-47 °C.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this material at a typical assay of 97% as a research/technical-grade synthetic reagent. We do not represent it as USP, BP or EP pharmacopoeial grade. A certificate of analysis can be provided with each batch on request.
What are the safety and handling hazards of 1-(3-Bromo-1-propynyl)naphthalene?
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It is classified Danger (GHS05, GHS07, GHS09) with hazard statements H315 (skin irritation), H318 (serious eye damage), H335 (may cause respiratory irritation) and H400 (very toxic to aquatic life). Handle with gloves, eye protection and an N95-type dust mask, avoid release to the environment, and consult the SDS before use.
How is 1-(3-Bromo-1-propynyl)naphthalene packed, shipped and exported?
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It is packed in tightly sealed, appropriately labelled containers with sizes matched to your requirement. As an environmentally hazardous substance it ships under UN 3082, Class 9, Packing Group III; we arrange compliant documentation and global export by suitable transport modes.
How do I request a sample or quote?
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Contact Tech Serve Solutions with your required quantity, purity and destination, and our team will respond with availability, lead time and export terms. Samples can be arranged subject to regulatory and transport requirements.
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