1-(3-Azetidinyl)-2-methylpiperidine
1-(3-Azetidinyl)-2-methylpiperidine (CAS 959239-81-7) is a saturated bicyclic diamine building block with the molecular formula C9H18N2 and a molar mass of 154.25 g/mol. It pairs a strained four-membered azetidine ring with a 2-methylpiperidine, giving two basic nitrogen centres and a defined three-dimensional scaffold. Tech Serve Solutions supplies it as a research-grade heterocyclic building block for chemical synthesis, medicinal-chemistry and discovery programmes that value sp3-rich amine cores.
- Synonyms
- 1-(3-Azetidinyl)-2-methylpiperidine1-(azetidin-3-yl)-2-methylpiperidine2-methyl-1-(azetidin-3-yl)piperidine2-methyl-1-(3-azetidinyl)piperidine

Heterocyclic building block
Serves as a compact, sp3-rich scaffold combining azetidine and piperidine rings. It is used to introduce three-dimensional character and basic nitrogen centres into more elaborate target molecules.
Medicinal-chemistry and discovery synthesis
Saturated azetidine-piperidine diamines are valued in drug-discovery libraries for improving solubility and shape diversity. The secondary azetidine N-H offers a convenient handle for analogue generation.
Amine functionalisation
The free azetidine nitrogen can undergo acylation, sulfonylation, reductive amination and related N-derivatisation. This makes the compound a practical intermediate for assembling amide, sulfonamide and alkylamine motifs.
Late-stage diversification and SAR studies
The rigid bicyclic core is well suited to structure-activity-relationship work where a defined diamine geometry is required. It supports parallel synthesis around a consistent central fragment.
| Molecular weight | 154.25 |
|---|---|
| Empirical formula | C9H18N2 |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-(3-Azetidinyl)-2-methylpiperidine used for?
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It is used as a heterocyclic building block in chemical synthesis and medicinal chemistry. The combined azetidine and 2-methylpiperidine rings provide an sp3-rich diamine scaffold with two basic nitrogen centres, useful for preparing more complex intermediates and analogue libraries.
What is the CAS number and molecular formula of 1-(3-Azetidinyl)-2-methylpiperidine?
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The CAS number is 959239-81-7. The molecular formula is C9H18N2, with a molecular weight of 154.25 g/mol.
What grade and purity does Tech Serve Solutions supply?
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We supply 1-(3-Azetidinyl)-2-methylpiperidine as a research- and synthesis-grade building block. It is not represented as USP, BP or EP pharmacopoeial grade. A current Certificate of Analysis stating the actual assay and batch specification is provided with each lot on request.
How should 1-(3-Azetidinyl)-2-methylpiperidine be handled and stored?
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Handle it as a research chemical using good laboratory practice: appropriate gloves, eye protection and adequate ventilation. As a basic amine it should be kept tightly closed, away from strong acids and oxidisers, and stored cool and dry. Always consult the Safety Data Sheet supplied with your shipment before use.
How is 1-(3-Azetidinyl)-2-methylpiperidine packed, shipped and exported?
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It is packed in suitably sealed, labelled containers sized from gram to bulk quantities to preserve integrity in transit. Each consignment ships with the relevant documentation, and Tech Serve Solutions exports worldwide in line with applicable transport and customs requirements.
How do I request a sample or quote?
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Contact Tech Serve Solutions with your required quantity, packaging and destination, quoting CAS 959239-81-7. We will respond with availability, lead time, specification and a formal quotation, and can arrange a sample where appropriate.
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