1-(3-Carboxyphenyl)-2-thiourea
1-(3-Carboxyphenyl)-2-thiourea (CAS 37182-75-5) is a crystalline organosulfur building block with the molecular formula C8H8N2O2S and a molar mass of 196.23 g/mol. It pairs a thiourea group with a meta-substituted benzoic acid ring, giving complementary hydrogen-bonding and acid functionality. Tech Serve Solutions supplies it as a research-grade reagent (assay 96%) for organic and heterocyclic synthesis, where it serves as an intermediate and a precursor to thiourea-derived scaffolds.
- Synonyms
- 1-(3-Carboxyphenyl)-2-thiourea3-(Thioureido)benzoic acidN-(3-Carboxyphenyl)thiourea3-(Carbamothioylamino)benzoic acidm-Thioureidobenzoic acid
Organic and heterocyclic building block
Used as a functionalised intermediate in synthetic chemistry, where the thiourea moiety supports cyclisation to heterocyclic systems such as thiazoles, aminothiazoles and related sulfur-nitrogen rings.
Precursor to thiourea derivatives
The reactive thiourea group is amenable to S-alkylation, condensation and desulfurisation, enabling access to substituted guanidines, isothioureas and further nitrogen-rich derivatives.
Carboxyl-bearing scaffold for conjugation
The pendant benzoic acid offers a handle for amide coupling, esterification and salt formation, making the molecule useful where a carboxylic acid anchor is required alongside a thiourea unit.
Hydrogen-bonding and coordination studies
Thiourea-functionalised benzoic acids of this type are of interest as ligands and hydrogen-bond donors in coordination chemistry, anion-binding and supramolecular research.
Laboratory research reagent
Supplied for method development and exploratory synthesis in academic and industrial laboratories that require a defined, characterised thiourea building block.
| Molecular weight | 196.23 |
|---|---|
| Linear formula | H2NC(S)NHC6H4CO2H |
| Assay | 96% |
| Melting point | 187-191 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-(3-Carboxyphenyl)-2-thiourea used for?
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It is used mainly as a building block and intermediate in organic and heterocyclic synthesis. The thiourea group enables cyclisation to sulfur-nitrogen heterocycles and conversion to related derivatives, while the benzoic acid functionality provides a site for coupling and salt formation. It is supplied for research and laboratory applications.
What is the CAS number and molecular formula of 1-(3-Carboxyphenyl)-2-thiourea?
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The CAS number is 37182-75-5 and the linear formula is H2NC(S)NHC6H4CO2H, corresponding to the molecular formula C8H8N2O2S. The molecular weight is 196.23 g/mol, the MDL number is MFCD00060450 and the reported melting point is 187-191 °C.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1-(3-Carboxyphenyl)-2-thiourea as a research/technical-grade reagent with a typical assay of 96%. We do not represent it as a USP, BP or EP pharmacopoeial grade. A certificate of analysis can be provided with each consignment to confirm the delivered specification.
What safety and handling precautions apply?
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Handle only with suitable personal protective equipment, including eye shields, gloves and an N95 (US) or P1 (EN143) respirator filter where dust may form. The substance carries a German Water Hazard Class of WGK 3, meaning it is severely hazardous to water, so contact with drains, soil and surface water must be prevented. Always consult the current Safety Data Sheet before use.
How is 1-(3-Carboxyphenyl)-2-thiourea packed, shipped and exported?
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It is packed as a solid in tightly sealed, appropriately labelled containers sized from research quantities to bulk, with packaging selected to keep the material dry and contained. Tech Serve Solutions exports worldwide with full documentation and a Safety Data Sheet, observing applicable transport and import requirements for the destination country.
How do I request a sample or quote?
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Contact Tech Serve Solutions with your required quantity, purity and destination, and our team will confirm availability, lead time and packaging. We can provide a certificate of analysis and Safety Data Sheet, and arrange samples or bulk supply for evaluation and ongoing requirements.
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