1α,25-Dihydroxyvitamin D2
1α,25-Dihydroxyvitamin D2 (CAS 60133-18-8) is a biologically active form of vitamin D2 with a molecular weight of 428.65 g/mol. This compound plays a crucial role in calcium and phosphate homeostasis, bone metabolism, and immune function. It is primarily utilised in cell biology research for studying vitamin D signalling pathways, metabolic processes, and its effects on various cellular functions within the realms of nutrition and steroid metabolism.
- IUPAC
- 1α,25-Dihydroxycalciferol
- Synonyms
- 1α,25-DihydroxycalciferolErgocalciferol, 1,25-dihydroxy-
Cell Biology Research
Investigates cellular mechanisms and signalling pathways related to vitamin D action. Used to study gene expression, cell differentiation, and proliferation in various cell types.
Metabolic Pathway Studies
Examines the biochemical transformations and regulation of vitamin D metabolism in biological systems. Crucial for understanding nutrient absorption and endocrine functions.
Nutrition Research
Aids in understanding the physiological impact of vitamin D2, particularly its role in calcium absorption and bone health. Supports research into dietary requirements and supplementation efficacy.
Steroid Metabolism Investigations
Serves as a key molecule in the study of steroid hormone synthesis and function. Explores its interplay with other steroidal compounds and metabolic pathways.
| Molecular weight | 428.65 |
|---|---|
| Empirical formula | C28H44O3 |
| Assay | ≥97.0% (sum of vitamin and previtamin, HPLC) |
| Storage temperature | −70°C |
Hazard statements
- H301Toxic if swallowed
- H311Toxic in contact with skin
- H331Toxic if inhaled
- H361Suspected of damaging fertility or the unborn child
Precautionary statements
- P260Do not breathe dust, fume, gas, mist, vapours or spray
- P280Wear protective gloves, clothing and eye/face protection
- P284Wear respiratory protection
- P301IF SWALLOWED
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 63-23/24/25 |
| Safety statements (S) | 36/37-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1α,25-Dihydroxyvitamin D2 used for?
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1α,25-Dihydroxyvitamin D2 is primarily used in scientific research, including cell biology, metabolic pathway studies, metabolomics, nutrition research, and steroid metabolism investigations. It helps researchers understand the biological functions and mechanisms of vitamin D action.
What are the CAS number and formula for 1α,25-Dihydroxyvitamin D2?
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The CAS number for 1α,25-Dihydroxyvitamin D2 is 60133-18-8. Its empirical formula (Hill notation) is C28H44O3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1α,25-Dihydroxyvitamin D2 with an assay of ≥97.0% (sum of vitamin and previtamin, HPLC). TSS does not represent this product as USP, BP, EP, or other pharmacopoeia grades unless explicitly stated.
How should 1α,25-Dihydroxyvitamin D2 be handled and stored?
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1α,25-Dihydroxyvitamin D2 is a highly toxic substance requiring extreme caution. Handle with appropriate personal protective equipment including eyeshields, face shields, gloves, and respiratory protection (N100 or P3 filters). Store at −70°C.
How is 1α,25-Dihydroxyvitamin D2 shipped or exported?
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1α,25-Dihydroxyvitamin D2 is classified as UN 2811, Class 6.1, Packing Group II, and is shipped and exported in accordance with stringent international regulations for hazardous materials.
How can I request a quote or sample for 1α,25-Dihydroxyvitamin D2?
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To request a quote or a sample of 1α,25-Dihydroxyvitamin D2, please contact our sales department through the TSS website or by phone, providing your specific requirements.
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