1α-Hydroxyvitamin D3
1α-Hydroxyvitamin D3 (CAS: 41294-56-8, C27H44O2) is a synthetic analog of vitamin D, characterized by a hydroxyl group at the 1α position. With a molecular weight of 400.64 g/mol, this compound plays a crucial role in calcium and phosphate homeostasis. It is widely utilised in research for studying metabolic pathways, cell biology, and nutritional science, particularly in investigations related to steroid and vitamin D metabolism.
- IUPAC
- 1α-Hydroxycholecalciferol,Alfacalcidol
- Synonyms
- 1α-HydroxycholecalciferolAlfacalcidol
Biochemical Research
Utilised as a standard and research tool in studies focusing on vitamin D metabolism, steroid biochemistry, and related endocrine pathways. Its structural similarity to natural vitamin D allows for investigations into its biological activity and mechanisms.
Cell Biology Studies
Employed in cell culture experiments to investigate the effects of vitamin D analogs on cellular differentiation, proliferation, and gene expression. It serves as a valuable reagent for understanding calcium signalling and bone metabolism at a cellular level.
Metabolic Pathway Investigations
Serves as a key compound in metabolomics and metabolic pathway research, aiding in the elucidation of biochemical routes involving vitamin D and its derivatives. It is instrumental in understanding disorders of calcium and phosphate regulation.
Nutrition Research
Applied in nutritional science research to explore the physiological impact of vitamin D supplementation and the roles of different vitamin D metabolites in maintaining health and preventing deficiency-related conditions.
| Molecular weight | 400.64 |
|---|---|
| Empirical formula | C27H44O2 |
| Assay | ≥97.0% (HPLC) |
| Storage temperature | −20°C |
Hazard statements
- H300Fatal if swallowed
Precautionary statements
- P260Do not breathe dust, fume, gas, mist, vapours or spray
- P264Wash thoroughly after handling
- P280Wear protective gloves, clothing and eye/face protection
- P284Wear respiratory protection
- P301IF SWALLOWED
- P302IF ON SKIN
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T+ |
| Risk statements (R) | 26/27/28 |
| Safety statements (S) | 28-36/37-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1α-Hydroxyvitamin D3 used for?
+
1α-Hydroxyvitamin D3 is primarily used in biochemical research, cell biology studies, metabolic pathway investigations, and nutrition research. It serves as a tool to study vitamin D metabolism, calcium and phosphate homeostasis, and related biological processes.
What is the CAS number and chemical formula for 1α-Hydroxyvitamin D3?
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The CAS number for 1α-Hydroxyvitamin D3 is 41294-56-8, and its chemical formula is C27H44O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1α-Hydroxyvitamin D3 with an assay of ≥97.0% (HPLC). TSS does not represent this product as USP, BP, EP, or pharmacopoeia grade.
How should 1α-Hydroxyvitamin D3 be handled and stored?
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1α-Hydroxyvitamin D3 is a highly toxic substance (Danger: H300 +H310 + H330) and requires stringent handling procedures. It should be stored at -20°C and handled with appropriate personal protective equipment, including eyeshields, face shields, gloves, and a full-face respirator (type N100 US or P3 EN143).
How is this chemical packed, shipped, and exported?
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This chemical is shipped and exported in compliance with regulations for hazardous materials (UN 2811 6.1 / PGII). Specific packaging details are available upon request to ensure safe transport.
How can I request a sample or quote for 1α-Hydroxyvitamin D3?
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To request a sample or obtain a quote for 1α-Hydroxyvitamin D3, please contact the Tech Serve Solutions sales department via our website or direct inquiry.
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