UK-78282 monohydrochloride
UK-78282 monohydrochloride (CAS: 136647-02-4) is a chemical compound with the formula C29H35NO2HCl and a molecular weight of 466.05 g/mol. Supplied as a white to off-white solid, this compound is primarily utilised in research settings. Its known applications span cell biology, cell signalling, and neuroscience, with a specific focus on its role as a modulator of voltage-gated ion channels, particularly potassium channels.
- IUPAC
- 4-[(Diphenylmethoxy)methyl]-1-[3-(4-methoxyphenyl)propyl]-piperidine monohydrochloride
Ion Channel Research
UK-78282 monohydrochloride is employed in the study of ion channels, including monovalent and voltage-gated types. It is specifically recognised for its activity as a potassium channel modulator.
Cell Biology and Signalling
This compound serves as a valuable tool in cell biology research, aiding in the investigation of cellular signalling pathways. Its mechanism of action involves modulating ion channel function, which is critical for cellular communication and function.
Neuroscience Applications
Within neuroscience, UK-78282 monohydrochloride is used to explore the roles of specific ion channels in neuronal function. Research may focus on how these channels influence neuronal excitability and signal transmission.
Drug Discovery and Development
As a compound identified within approved therapeutics/drug candidates, it may be utilised in early-stage drug discovery and development programmes, particularly those targeting ion channelopathies or related neurological conditions.
| Molecular weight | 466.05 |
|---|---|
| Empirical formula | C29H35NO2HCl |
| Assay | ≥98% (HPLC) |
| Form | solid |
| Colour | white to off-white |
| Solubility | DMSO: >10 mg/mL |
| Storage temperature | −20°C |
Hazard statements
- H319Causes serious eye irritation
- H400Very toxic to aquatic life
Precautionary statements
- P273Avoid release to the environment
- P305IF IN EYES
| Transport (UN / ADR) | UN 3077 9 / PGIII |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi,N |
| Risk statements (R) | 36-50/53 |
| Safety statements (S) | 26-60-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Shipped In | wet ice |
|---|---|
| Storage Condition | desiccated |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is UK-78282 monohydrochloride used for?
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UK-78282 monohydrochloride is used in scientific research, particularly in the fields of cell biology, cell signalling, neuroscience, and ion channel studies. It is recognised as a potassium channel modulator and is associated with voltage-gated ion channels.
What are the CAS number and formula for UK-78282 monohydrochloride?
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The CAS number for UK-78282 monohydrochloride is 136647-02-4, and its empirical formula is C29H35NO2HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies UK-78282 monohydrochloride with a purity of ≥98% as determined by HPLC. TSS does not represent this product as USP, BP, EP, or other pharmacopoeial grades.
What are the safety and handling precautions for UK-78282 monohydrochloride?
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UK-78282 monohydrochloride is classified as a GHS07 and GHS09 substance with a 'Warning' signal word. It carries hazard statements H319 (causes serious eye irritation) and H400 (very toxic to aquatic life). Handle with appropriate personal protective equipment, avoid release to the environment, and follow safety statements such as P273 and P305 + P351 + P338.
How is UK-78282 monohydrochloride shipped and stored?
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This product is shipped in wet ice and should be stored under desiccated conditions at -20°C to maintain its stability.
How can I request a quote or sample for UK-78282 monohydrochloride?
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To request a quote or sample of UK-78282 monohydrochloride, please contact our sales team via the website or by phone.
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