19-Norethindrone
19-Norethindrone (CAS: 68-22-4; Formula: C20H26O2) is a synthetic progestogen, a derivative of the hormone progesterone. It is a white to off-white powder with a molecular weight of 298.42 g/mol. Primarily utilised in pharmaceutical research and development, it serves as a key component in the study of reproductive endocrinology and hormonal regulation. Its well-defined chemical structure and purity make it suitable for advanced biochemical investigations.
- IUPAC
- 17α-Ethynyl-19-nortestosterone,17-Hydroxy-19-nor-17α-4-pregnen-20-yn-3-one,17α-Ethynyl-17β-hydroxy-19-nor-4-androsten-3-one,19-Nor-17α-ethynyl-4-androsten-17β-ol-3-one,19-Norethisterone
- Synonyms
- 17α-Ethynyl-19-nortestosterone17-Hydroxy-19-nor-17α-4-pregnen-20-yn-3-one17α-Ethynyl-17β-hydroxy-19-nor-4-androsten-3-one19-Nor-17α-ethynyl-4-androsten-17β-ol-3-one19-Norethisterone

Pharmaceutical Research
19-Norethindrone is extensively used in research laboratories for studying hormonal pathways, particularly those related to reproductive health and endocrinology. Its properties as a synthetic progestogen make it a valuable tool for investigating hormone-receptor interactions and developing new therapeutic agents.
Biochemical Investigations
This compound serves as a reference standard and research chemical in biochemical assays and cell signalling studies. Researchers utilise it to understand the mechanisms of steroid hormone action and its impact on various cellular processes.
Endocrinology Studies
As a potent progestogen, 19-Norethindrone is instrumental in studies focused on the endocrine system, particularly in understanding the female reproductive cycle and the development of contraceptives and hormone replacement therapies.
| Molecular weight | 298.42 |
|---|---|
| Empirical formula | C20H26O2 |
| Assay | ≥98% |
| Form | powder |
| Colour | white to off-white |
| Solubility | chloroform: ≥50 mg/mL, clear, colorless |
| Melting point | 205-206 °C(lit.) |

Hazard statements
- H351Suspected of causing cancer
Precautionary statements
- P281Use personal protective equipment as required
| Protective equipment | Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 40 |
| Safety statements (S) | 22-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... AR(367), PGR(5241)rat ... Ar(24208) |
|---|---|
| Storage Condition | protect from light |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 19-Norethindrone used for?
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19-Norethindrone is used in pharmaceutical research and biochemical investigations, particularly for studying hormonal pathways related to reproductive health and endocrinology.
What are the CAS number and formula for 19-Norethindrone?
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The CAS number for 19-Norethindrone is 68-22-4, and its formula is C20H26O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 19-Norethindrone with an assay of ≥98%. We do not represent this product as USP, BP, EP, or pharmacopoeia grade unless explicitly stated otherwise.
What are the primary safety concerns when handling 19-Norethindrone?
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19-Norethindrone is classified with GHS08 symbol and a 'Warning' signal word. It carries the hazard statement H351 (Suspected of causing cancer). Appropriate personal protective equipment, including eyeshields, gloves, and suitable respirators (e.g., N100 or P3 filters), should be used. Handle with care in a well-ventilated area, and protect from light during storage.
How is 19-Norethindrone packed and exported?
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19-Norethindrone is typically supplied as a powder and is carefully packed to ensure its integrity during transit. Tech Serve Solutions exports chemicals globally, adhering to all relevant shipping regulations.
How can I request a quote or sample for 19-Norethindrone?
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To request a quote or sample for 19-Norethindrone, please contact our sales team through the website or by phone, providing your specific requirements and shipping details.
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