17α-Hydroxypregnenolone
17α-Hydroxypregnenolone (CAS 387-79-1), with the molecular formula C21H32O3 and a molecular weight of 332.48 g/mol, is a steroid hormone. It functions as a precursor in the biosynthesis of various steroid hormones and plays a role in metabolic pathways, particularly steroid metabolism. It is also recognised for its involvement in cell signalling and neurobiological processes, including neurotransmission. This compound is a valuable research chemical for studies in endocrinology and cell biology.
- IUPAC
- 3β,17α-Dihydroxy-5-pregnen-20-one,5-Pregnene-3β,17α-diol-20-one
- Synonyms
- 5-Pregnene-3,17-diol-20-one3β,17α-Dihydroxy-5-pregnen-20-one

Endocrine Research
Utilised in studies investigating steroidogenesis and the biosynthesis pathways of various hormones. It serves as a key intermediate in understanding hormonal regulation.
Neuroscience Studies
Applied in research focused on neurosteroids and their modulation of neurotransmission, particularly concerning GABA and glycine receptor activity.
Metabolic Pathway Analysis
Serves as a tool for researchers exploring metabolic pathways, with a specific focus on steroid metabolism and metabolomics.
Cell Biology Investigations
Employed in cell signalling research to understand the complex interactions and regulatory mechanisms within biological systems.
| Molecular weight | 332.48 |
|---|---|
| Empirical formula | C21H32O3 |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 17α-Hydroxypregnenolone used for?
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17α-Hydroxypregnenolone is primarily used in research for investigating endocrine functions, steroidogenesis, metabolic pathways, and neurobiological processes related to neurotransmission.
What is the CAS number and molecular formula for 17α-Hydroxypregnenolone?
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The CAS number is 387-79-1 and the molecular formula is C21H32O3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 17α-Hydroxypregnenolone with a minimum purity of 98%. This product is intended for research and laboratory use; TSS does not represent it as USP, BP, or EP grade.
What are the safety considerations when handling 17α-Hydroxypregnenolone?
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When handling 17α-Hydroxypregnenolone, it is essential to use personal protective equipment including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter. Refer to the safety data sheet for comprehensive handling guidelines.
How is 17α-Hydroxypregnenolone packed and shipped?
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17α-Hydroxypregnenolone is carefully packed according to industry standards to ensure safe transit and is available for global export by Tech Serve Solutions.
How can I request a sample or quote for 17α-Hydroxypregnenolone?
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To request a sample or a quotation for 17α-Hydroxypregnenolone, please contact our sales team through the website or by phone, referencing the product CAS number 387-79-1.
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