17α-Ethynylestradiol 3-cyclopentyl ether
17α-Ethynylestradiol 3-cyclopentyl ether (CAS: 152-43-2, Formula: C25H32O2) is a synthetic estrogen derivative with a molecular weight of 364.52 g/mol. This compound primarily functions as a research chemical in cell biology and cell signaling studies, particularly within the realms of endocrinology and neuroscience. It is recognised for its role in investigations involving hormone receptor interactions and downstream cellular responses.
- IUPAC
- 17α-Ethynyl-1,3,5(10)-estratriene-3,17β-diol 3-cyclopentyl ether,Quinestrol
- Synonyms
- Quinestrol

Endocrine Research
Utilised in studies investigating estrogenic activity and its impact on cellular pathways. Its synthetic nature allows for controlled experiments in hormone research.
Cell Signaling Investigations
Serves as a tool to probe cellular signaling cascades regulated by estrogen receptors. Useful in understanding the molecular mechanisms of hormone action in various cell types.
Neuroscience Studies
Applied in research examining the neuroprotective or neuromodulatory effects of estrogens. Helps to elucidate the role of steroid hormones in the central nervous system.
Hormone Receptor Studies
A valuable reagent for characterising estrogen receptor binding affinity and downstream gene expression. Facilitates research into hormone-dependent biological processes.
| Molecular weight | 364.52 |
|---|---|
| Empirical formula | C25H32O2 |


Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H332Harmful if inhaled
- H350May cause cancer
- H360May damage fertility or the unborn child
Precautionary statements
- P201Obtain special instructions before use
- P280Wear protective gloves, clothing and eye/face protection
- P308IF exposed or concerned
| Protective equipment | Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 45-61-20/21/22 |
| Safety statements (S) | 53-22-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 17α-Ethynylestradiol 3-cyclopentyl ether used for?
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17α-Ethynylestradiol 3-cyclopentyl ether is primarily used as a research chemical in areas such as cell biology, cell signaling, neuroscience, and endocrine research, particularly for studies involving estrogen receptors and hormone action.
What are the CAS number and chemical formula?
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The CAS number for 17α-Ethynylestradiol 3-cyclopentyl ether is 152-43-2, and its chemical formula is C25H32O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 17α-Ethynylestradiol 3-cyclopentyl ether as a research-grade chemical. Specific purity details are available on the product's Certificate of Analysis. TSS does not represent this product as USP, BP, or EP grade.
How should 17α-Ethynylestradiol 3-cyclopentyl ether be handled?
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Handling requires stringent safety measures due to significant hazards including danger of serious damage to health from exposure (H350, H360) and harmful if swallowed, in contact with skin, or if inhaled (H302, H312, H332). Use appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator (e.g., N100 type US), and work in a well-ventilated area or fume hood.
Is 17α-Ethynylestradiol 3-cyclopentyl ether a controlled substance?
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While not explicitly listed as a controlled substance in all jurisdictions, its classification as a synthetic estrogen derivative with potential reproductive toxicity (H360) necessitates careful handling and adherence to all relevant regulations regarding its procurement and use.
How is 17α-Ethynylestradiol 3-cyclopentyl ether packaged and exported?
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This chemical is carefully packaged to ensure stability and safety during transit. Tech Serve Solutions is experienced in exporting fine chemicals globally, adhering to international shipping regulations.
How can I request a sample or quote?
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To request a sample or quote for 17α-Ethynylestradiol 3-cyclopentyl ether, please contact our sales department through the website or by calling our direct line.
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