1,2-Distearoyl-sn-glycero-3-phosphocholine
1,2-Distearoyl-sn-glycero-3-phosphocholine (CAS: 816-94-4), also known as DSPC, is a high-purity phospholipid with a molecular weight of 790.15 g/mol. This synthetic lipid is a key component in cell membrane research and the formulation of advanced drug delivery systems, particularly liposomes. Its saturated fatty acid chains contribute to the stability of lipid bilayers. DSPC is widely utilised in biochemical studies and pharmaceutical development.
- IUPAC
- 1,2-Dioctadecanoyl-sn-glycero-3-phosphocholine,3-sn-Phosphatidylcholine, 1,2-distearoyl,L-α-Phosphatidylcholine, distearoyl,L-β,γ-Distearoyl-α-lecithin,DSPC,PC(18:0/18:0)
- Synonyms
- C44H88NO8P1,2-Dioctadecanoyl-sn-glycero-3-phosphocholine3-sn-Phosphatidylcholine, 1,2-distearoylL-α-Phosphatidylcholine, distearoylL-β,γ-Distearoyl-α-lecithinDSPCPC(18:0/18:0)
Liposome Formulation
DSPC is a critical excipient for creating stable and well-defined liposomes. It forms the bilayer structure, contributing to the encapsulation efficiency and circulation half-life of therapeutic agents.
Drug Delivery Systems
Its excellent phase transition properties make DSPC suitable for controlled-release drug formulations. It is used to engineer delivery vehicles for both small molecules and nucleic acids.
Membrane Research
As a natural component of cell membranes, DSPC is used in biophysical studies to understand membrane structure, dynamics, and protein-lipid interactions.
Biochemical Reagent
This compound serves as a valuable reagent in various biochemical assays and experiments requiring well-characterised phospholipids for accurate results.
| Molecular weight | 790.15 |
|---|---|
| Empirical formula | C44H88NO8P |
| Assay | ≥99.0% (TLC) |
| Storage temperature | −20°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Shipped In | wet ice |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1,2-Distearoyl-sn-glycero-3-phosphocholine used for?
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1,2-Distearoyl-sn-glycero-3-phosphocholine (DSPC) is primarily used in liposome formulation, advanced drug delivery systems, and for research into cell membrane structure and function. It serves as a key component in creating stable lipid bilayers for various biochemical and pharmaceutical applications.
What is the CAS number and formula for 1,2-Distearoyl-sn-glycero-3-phosphocholine?
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The CAS number for 1,2-Distearoyl-sn-glycero-3-phosphocholine is 816-94-4. Its empirical formula (Hill notation) is C44H88NO8P.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1,2-Distearoyl-sn-glycero-3-phosphocholine with an assay of ≥99.0% as determined by TLC. This product is intended for research and technical use and is not represented as USP, BP, EP, or other pharmacopoeial grades.
How should 1,2-Distearoyl-sn-glycero-3-phosphocholine be handled and stored?
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Handle 1,2-Distearoyl-sn-glycero-3-phosphocholine with appropriate personal protective equipment, including eyeshields and gloves. A respirator filter of type N95 (US) or P1 (EN143) is recommended. Store the compound at -20°C, shipped in wet ice.
Is 1,2-Distearoyl-sn-glycero-3-phosphocholine a controlled substance?
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Based on the provided data, 1,2-Distearoyl-sn-glycero-3-phosphocholine is not listed as a controlled substance. Its WGK Germany classification is 3.
How is 1,2-Distearoyl-sn-glycero-3-phosphocholine shipped?
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This product is shipped in wet ice to maintain its integrity during transport.
How can I request a sample or quote for 1,2-Distearoyl-sn-glycero-3-phosphocholine?
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Please contact the Tech Serve Solutions sales team directly through our website or by phone to request a sample or a formal quotation for 1,2-Distearoyl-sn-glycero-3-phosphocholine.
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