1,2-Bis(trimethylsiloxy)ethane
1,2-Bis(trimethylsiloxy)ethane, CAS 7381-30-8, with a molecular weight of 206.43 g/mol, is a versatile organic building block. This silylated derivative of ethylene glycol serves as a protected diol, finding utility in various chemical synthesis pathways. Its properties make it a valuable reagent in organic chemistry research and development, particularly for introducing protected ethylene glycol units into larger molecules.
- IUPAC
- Ethylene glycol bis(trimethylsilyl ether)
- Synonyms
- (CH3)3SiOCH2CH2OSi(CH3)3Ethylene glycol bis(trimethylsilyl ether)

Organic Synthesis
Utilised as a protected form of ethylene glycol, facilitating reactions where the hydroxyl groups need to be temporarily masked. It is employed in the construction of more complex organic molecules.
Building Block for Complex Molecules
Serves as a key intermediate in multi-step syntheses, allowing for precise introduction of the bis(trimethylsiloxy)ethane moiety. This is critical in areas requiring specific functional group manipulation.
Research and Development
A standard reagent in academic and industrial laboratories for exploring new synthetic routes and developing novel compounds. Its predictable reactivity makes it suitable for various organic transformations.
| Molecular weight | 206.43 |
|---|---|
| Linear formula | (CH3)3SiOCH2CH2OSi(CH3)3 |
| Assay | 98% |
| Boiling point | 165-166 °C(lit.) |
| Density | 0.842 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.403(lit.) |

Hazard statements
- H226Flammable liquid and vapour
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 51 °C / 123.8 °F |
| Transport (UN / ADR) | UN 1993C 3 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Risk statements (R) | 10 |
| Safety statements (S) | 23-24/25 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1,2-Bis(trimethylsiloxy)ethane used for?
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1,2-Bis(trimethylsiloxy)ethane (CAS 7381-30-8) is primarily used as a protected form of ethylene glycol in organic synthesis and as a building block for constructing complex organic molecules in research and development.
What is the CAS number and molecular formula for 1,2-Bis(trimethylsiloxy)ethane?
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The CAS number is 7381-30-8, and its linear formula is (CH3)3SiOCH2CH2OSi(CH3)3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1,2-Bis(trimethylsiloxy)ethane with an assay of 98%. We do not represent this product as USP, BP, EP or other pharmacopoeia grades.
What are the safety and handling precautions for 1,2-Bis(trimethylsiloxy)ethane?
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This compound is a flammable liquid and vapour (H226). Handle with appropriate personal protective equipment, including eyeshields, face shield, gloves, and a suitable respirator. Ensure adequate ventilation and keep away from heat, sparks, and open flames.
How is 1,2-Bis(trimethylsiloxy)ethane packed, shipped, and exported?
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1,2-Bis(trimethylsiloxy)ethane is shipped according to its hazard classification (UN 1993, Class 3, Packing Group III). TSS ensures all shipments comply with international shipping and export regulations for hazardous materials.
How can I request a quote or sample for 1,2-Bis(trimethylsiloxy)ethane?
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To request a quote or sample, please contact our sales team through the TSS website or by phone, providing the product name (1,2-Bis(trimethylsiloxy)ethane) and CAS number (7381-30-8).
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