3,3-Dimethylglutarimide
3,3-Dimethylglutarimide (CAS: 1123-40-6), a heterocyclic organic compound with the molecular formula C7H11NO2 and a molecular weight of 141.17 g/mol, serves as a valuable building block in organic synthesis. It is frequently employed as a reactant for the development of novel pharmaceutical agents, including spiro-piperidine inhibitors and selective inhibitors for viral proteases. Its utility extends to the creation of various complex organic structures.
- IUPAC
- 4,4-Dimethyl-2,6-piperidinedione
- Synonyms
- 4,4-Dimethyl-2,6-piperidinedione
Pharmaceutical Intermediate
Used as a reactant in the synthesis of spiro-piperidine inhibitors targeting influenza A virus M2 proton channels. It is also a precursor for second-generation selective inhibitors of Hepatitis C virus NS3 serine protease.
Organic Synthesis Building Block
Facilitates the synthesis of spirocyclic oxetanes and complex heterocyclic structures. It is also employed in Ru-catalyzed stereoselective additions of imides to alkynes.
Neuroscience Research
Acts as a building block for metabolically protected arylpiperazine 5-HT1A ligands, useful in neuroscience research. Additionally, it is used in the development of selective antagonists for the a1d adrenergic receptor.
| Molecular weight | 141.17 |
|---|---|
| Empirical formula | C7H11NO2 |
| Assay | 99% |
| Application | Reactant for synthesis of:• Spiro-piperidine inhibitors for modulation of the M2 proton channel from influenza A virus1• Second-generation selective inhibitors of Hepatitis C virus NS3 serine protease2• Spirocyclic oxetanes3• Ru-catalyzed stereoselective addition of imides to alkynes4• Metabolically protected arylpiperiazine 5-HT1A ligands5• Selective antagonists of the a1d adrenergic receptor6 |
| Melting point | 144-146 °C(lit.) |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H317May cause an allergic skin reaction
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38-43 |
| Safety statements (S) | 26-36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3,3-Dimethylglutarimide used for?
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3,3-Dimethylglutarimide is used as a reactant in the synthesis of various pharmaceutical agents, including inhibitors for influenza and Hepatitis C viruses, spirocyclic compounds, and ligands for neurological research.
What is the CAS number and chemical formula for 3,3-Dimethylglutarimide?
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The CAS number for 3,3-Dimethylglutarimide is 1123-40-6, and its empirical formula is C7H11NO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3,3-Dimethylglutarimide with a purity of 99%. This product is supplied for research and chemical synthesis purposes and is not represented as USP, BP, EP, or any other pharmacopoeia grade.
What are the safety considerations when handling 3,3-Dimethylglutarimide?
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3,3-Dimethylglutarimide is a Warning substance. It can be harmful if swallowed (H302), causes skin irritation (H315), may cause an allergic skin reaction (H317), causes serious eye irritation (H319), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including a dust mask (N95), eyeshields, faceshields, and gloves, should be used.
Is 3,3-Dimethylglutarimide a controlled substance?
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The provided data does not indicate that 3,3-Dimethylglutarimide is a controlled substance.
How is 3,3-Dimethylglutarimide packed and exported?
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3,3-Dimethylglutarimide is carefully packed to ensure safe transit and is available for export globally by Tech Serve Solutions.
How can I request a sample or quote for 3,3-Dimethylglutarimide?
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To request a sample or a quote for 3,3-Dimethylglutarimide, please contact our sales department through the website or by phone, providing your specific requirements.
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