Tris(trimethylsilyl)phosphine
Tris(trimethylsilyl)phosphine (CAS: 15573-38-3), with the formula [(CH3)3Si]3P and a molecular weight of 250.54 g/mol, is a versatile organophosphorus compound. It serves as a key building block and ligand in organometallic chemistry and catalysis. Its unique structure, featuring silyl-protected phosphorus, makes it valuable for synthesizing more complex phosphine derivatives and in reactions requiring a sterically hindered, electron-rich phosphorus source.
- IUPAC
- Tris(trimethylsilyl)phosphane
![Tris(trimethylsilyl)phosphine ([(CH3)3Si]3P) — chemical structure, CAS 15573-38-3; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F15573-38-3.png&w=3840&q=75)
Ligand Synthesis
Tris(trimethylsilyl)phosphine is employed in the synthesis of specialized phosphine ligands for homogeneous catalysis. The trimethylsilyl groups can be selectively removed, allowing for controlled functionalization of the phosphorus atom.
Organometallic Chemistry
It serves as a precursor or reactant in organometallic chemistry, enabling the formation of novel metal-phosphine complexes. These complexes find applications in various catalytic transformations.
Chemical Synthesis
This compound is utilised as a reagent in organic synthesis for introducing phosphorus into molecules. Its silyl groups offer unique reactivity and solubility characteristics for synthetic pathways.
| Molecular weight | 250.54 |
|---|---|
| Linear formula | [(CH3)3Si]3P |
| Assay | 95% |
| Boiling point | 243-244 °C(lit.) |
| Density | 0.863 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.502(lit.) |
| Storage temperature | 2-8°C |


Hazard statements
- H250Catches fire spontaneously if exposed to air
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P222Do not allow contact with air
- P231Handle under inert gas
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
- P422
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Transport (UN / ADR) | UN 2845 4.2 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xi |
| Risk statements (R) | 17-36/37/38 |
| Safety statements (S) | 16-26-27-28-36/37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Tris(trimethylsilyl)phosphine used for?
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Tris(trimethylsilyl)phosphine is primarily used in chemical synthesis and organometallic chemistry, particularly for the preparation of phosphine ligands and the introduction of phosphorus into organic molecules. It serves as a valuable building block in catalysis.
What is the CAS number and formula for Tris(trimethylsilyl)phosphine?
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The CAS number for Tris(trimethylsilyl)phosphine is 15573-38-3, and its linear formula is [(CH3)3Si]3P.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Tris(trimethylsilyl)phosphine with an assay of 95%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should Tris(trimethylsilyl)phosphine be handled safely?
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Tris(trimethylsilyl)phosphine is highly flammable and pyrophoric, igniting spontaneously in air (H250). It causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Handle under an inert atmosphere, wearing appropriate personal protective equipment including eyeshields, gloves, and a full-face respirator.
Is Tris(trimethylsilyl)phosphine a controlled substance?
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The provided data does not indicate that Tris(trimethylsilyl)phosphine is a controlled substance.
How is Tris(trimethylsilyl)phosphine packed and shipped?
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Tris(trimethylsilyl)phosphine is packed and shipped according to regulations for pyrophoric substances (UN 2845 4.2), typically under an inert atmosphere. We export globally, adhering to all international shipping standards.
How can I request a sample or quote for Tris(trimethylsilyl)phosphine?
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To request a sample or a quote for Tris(trimethylsilyl)phosphine, please contact our sales department through the website or by phone.
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