Tris(4-methoxy-3,5-dimethylphenyl)phosphine
Tris(4-methoxy-3,5-dimethylphenyl)phosphine (CAS 121898-64-4) is a specialised organophosphorus compound with the molecular formula C27H33O3P and a molecular weight of 436.52 g/mol. This phosphine ligand finds application as a catalyst in organic synthesis, particularly for carbocyanation reactions of alkynes. Supplied by Tech Serve Solutions, it is available at a minimum assay of 97%.
- Synonyms
- C27H33O3P

Catalyst for Carbocyanation Reactions
Tris(4-methoxy-3,5-dimethylphenyl)phosphine serves as an effective catalyst in the carbocyanation of alkynes. This reaction is crucial for constructing complex organic molecules with specific carbon-carbon bond formations.
Phosphine Ligand in Catalysis
As a sterically hindered phosphine ligand, it can be employed in various transition metal-catalyzed reactions. Its unique electronic and steric properties influence catalyst activity and selectivity.
Intermediate in Chemical Synthesis
The compound can be utilised as a building block or reagent in multi-step organic syntheses, contributing to the development of novel chemical entities and materials.
| Molecular weight | 436.52 |
|---|---|
| Empirical formula | C27H33O3P |
| Assay | 97% |
| Application | Catalyst for carbocyanation of alkynes1 |
| Melting point | 174-179 °C |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
- H413May cause long-lasting harmful effects to aquatic life
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Tris(4-methoxy-3,5-dimethylphenyl)phosphine used for?
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Tris(4-methoxy-3,5-dimethylphenyl)phosphine is primarily used as a catalyst, specifically for the carbocyanation of alkynes, and as a phosphine ligand in various catalytic applications within chemical synthesis.
What is the CAS number and formula for Tris(4-methoxy-3,5-dimethylphenyl)phosphine?
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The CAS number is 121898-64-4, and the empirical formula is C27H33O3P.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Tris(4-methoxy-3,5-dimethylphenyl)phosphine with a minimum assay of 97%. This product is not represented as USP, BP, or EP grade.
How should Tris(4-methoxy-3,5-dimethylphenyl)phosphine be handled?
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Handling requires appropriate personal protective equipment, including a dust mask (type N95 or equivalent), eyeshields, and gloves. Ensure adequate ventilation and avoid breathing dust. The compound is labelled with hazard statements H315, H319, H335, and H413, indicating skin irritation, eye irritation, respiratory irritation, and potential for long-term adverse effects in the aquatic environment.
How is Tris(4-methoxy-3,5-dimethylphenyl)phosphine packed and shipped?
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This chemical is carefully packed to ensure integrity during transit and is available for global export by Tech Serve Solutions.
How can I request a sample or quote for Tris(4-methoxy-3,5-dimethylphenyl)phosphine?
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To request a sample or obtain a quotation, please contact the Tech Serve Solutions sales team through the website or designated contact channels.
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