Thallium(III) trifluoroacetate
Thallium(III) trifluoroacetate (CAS: 23586-53-0), with the linear formula (CF₃COO)₃Tl and a molecular weight of 543.43 g/mol, is a potent oxidizing agent. It is primarily utilised in specialised organic synthesis, particularly for the preparation of cysteine-containing peptides and proteins. Its effectiveness as an oxidising agent makes it a valuable reagent in specific chemical transformations requiring precise control.
- IUPAC
- TTFA,Thallic trifluoroacetate,Trifluoroacetic acid thallium(III) salt,Tris(trifluoroacetato)thallium
- Synonyms
- TTFAThallic trifluoroacetateTrifluoroacetic acid thallium(III) saltTris(trifluoroacetato)thallium
Peptide Synthesis
Thallium(III) trifluoroacetate serves as an oxidising agent in the synthesis of S-substituted cysteine peptides. This application is crucial for constructing complex peptide structures with specific modifications.
Protein Chemistry
It is employed in the synthesis of proteins that contain disulfide bonds. This capability aids in the study and production of biologically relevant protein structures.
Chemical Synthesis Reagent
As a strong oxidizing agent, it finds utility in various chemical synthesis pathways where controlled oxidation is required. Its specific reactivity profile is valuable in advanced organic chemistry.
| Molecular weight | 543.43 |
|---|---|
| Linear formula | (CF3COO)3Tl |
| Storage temperature | 2-8°C |
| Application | Oxidizing agent used in the synthesis of S-substituted cysteine peptides1 and proteins containing disulfide bonds.2 |
| Melting point | 213 °C (dec.)(lit.) |
Hazard statements
- H300Fatal if swallowed
- H330Fatal if inhaled
- H373May cause damage to organs through prolonged exposure
- H411Toxic to aquatic life with long-lasting effects
Precautionary statements
- P260Do not breathe dust, fume, gas, mist, vapours or spray
- P264Wash thoroughly after handling
- P273Avoid release to the environment
- P284Wear respiratory protection
- P301IF SWALLOWED
- P310Immediately call a POISON CENTER or doctor
| Transport (UN / ADR) | UN 1707 6.1 / PGII |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T+,N |
| Risk statements (R) | 26/28-33-51/53 |
| Safety statements (S) | 13-28-45-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Thallium(III) trifluoroacetate used for?
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Thallium(III) trifluoroacetate is used as an oxidizing agent, particularly in the synthesis of S-substituted cysteine peptides and proteins containing disulfide bonds.
What is the CAS number and formula for Thallium(III) trifluoroacetate?
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The CAS number is 23586-53-0 and the linear formula is (CF₃COO)₃Tl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Thallium(III) trifluoroacetate typically as a research or technical grade chemical. We do not represent it as USP, BP, or EP grade unless explicitly stated otherwise for a specific product listing. Please refer to the product's Certificate of Analysis for precise purity details.
How should Thallium(III) trifluoroacetate be handled?
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Thallium(III) trifluoroacetate is highly toxic (Danger, H300, H330) and may cause long-term adverse effects in the aquatic environment (H411). Handle with extreme caution in a well-ventilated area or fume hood, using appropriate personal protective equipment including gloves, eye protection, and respiratory protection. Avoid ingestion, inhalation, and contact with skin and eyes. Dispose of waste according to regulations.
Is Thallium(III) trifluoroacetate a controlled substance?
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While the provided data does not explicitly state it is a controlled substance, thallium compounds are highly toxic and subject to stringent regulations regarding handling, use, and disposal. Users should comply with all local and international regulations pertaining to toxic substances.
How is Thallium(III) trifluoroacetate packed and shipped?
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Thallium(III) trifluoroacetate is packed and shipped in accordance with international regulations for hazardous materials. UN 1707, Hazard Class 6.1, Packing Group II applies. TSS is experienced in exporting such chemicals globally.
How can I request a sample or quote?
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To request a sample or a quote for Thallium(III) trifluoroacetate, please contact our sales department via the website or direct email, providing your specific requirements.
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