N-(3-((3-((tert-Butyldimethylsilyloxy)methyl)pyrrolidin-1-yl)methyl)-2-chloropyridin-4-yl)pivalamide
N-(3-((3-((tert-Butyldimethylsilyloxy)methyl)pyrrolidin-1-yl)methyl)-2-chloropyridin-4-yl)pivalamide (CAS 1186310-83-7) is a multifunctional heterocyclic building block with the molecular formula C22H38ClN3O2Si and a molecular weight of 440.09 g/mol. It combines a 2-chloropyridine core, a substituted pyrrolidine and a tert-butyldimethylsilyl (TBS) ether, with the pivalamide acting as a protecting group. Tech Serve Solutions supplies it as a research-grade intermediate for chemical synthesis and pharmaceutical research.
- Synonyms
- N-(3-((3-((tert-Butyldimethylsilyloxy)methyl)pyrrolidin-1-yl)methyl)-2-chloropyridin-4-yl)pivalamideN-[3-[[3-[[[tert-butyl(dimethyl)silyl]oxy]methyl]pyrrolidin-1-yl]methyl]-2-chloropyridin-4-yl]-2,2-dimethylpropanamideCAS 1186310-83-7
Pharmaceutical intermediate
Serves as an advanced building block in the multi-step synthesis of pharmaceutical candidates and active ingredients. Its pre-assembled pyridine, pyrrolidine and silyl-protected hydroxymethyl groups shorten complex synthetic routes.
Heterocyclic building block
The 2-chloropyridine and pyrrolidine scaffolds are versatile platforms for medicinal-chemistry and discovery programmes. The chloro substituent provides a reactive handle for cross-coupling and nucleophilic substitution to extend molecular complexity.
Protected hydroxyl intermediate
The tert-butyldimethylsilyl (TBS) ether masks a primary alcohol during synthesis and can be selectively removed under standard desilylation conditions, allowing controlled, stepwise functional-group manipulation.
Organosilicon reagent
As an organosilicon compound, it supports orthogonal protecting-group strategies in route design where a robust, selectively cleavable silyl ether is required alongside other functional groups.
Research and development
Used in laboratory-scale research, process-development and structure-activity studies where a defined, characterised C16+ building block is needed. Supplied for research and manufacturing use only.
| Molecular weight | 440.09 |
|---|---|
| Empirical formula | C22H38ClN3O2Si |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N-(3-((3-((tert-Butyldimethylsilyloxy)methyl)pyrrolidin-1-yl)methyl)-2-chloropyridin-4-yl)pivalamide used for?
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It is used mainly as a heterocyclic building block and intermediate in chemical synthesis and pharmaceutical research. The combination of a 2-chloropyridine ring, a pyrrolidine bearing a TBS-protected hydroxymethyl group, and a pivalamide makes it useful for building more complex molecules through cross-coupling, substitution and selective deprotection.
What is the CAS number and molecular formula of this compound?
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The CAS number is 1186310-83-7. The molecular formula is C22H38ClN3O2Si (Hill notation), with a molecular weight of 440.09 g/mol.
What grade and purity does Tech Serve Solutions supply?
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It is supplied as a technical / research-grade building block for synthesis and laboratory use, with the actual assay confirmed on the batch Certificate of Analysis that accompanies each shipment. We do not represent this material as USP, BP or EP pharmacopoeial grade. Please request the current specification for your intended application.
How should this compound be handled and stored?
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No harmonised GHS classification is provided with this product, so handle it as a research chemical of undefined hazard: work in a fume hood, wear suitable gloves, eye protection and a lab coat, and avoid skin contact, ingestion and inhalation of dust. As an organosilicon ether it is moisture-sensitive, so store it tightly closed in a cool, dry, well-ventilated place. Always consult the Safety Data Sheet supplied with the consignment before use.
How is this product packed, shipped and exported?
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The material is packed in sealed, appropriately labelled laboratory containers sized to the order, with full batch documentation including a Certificate of Analysis and Safety Data Sheet. As a global supplier and exporter since 1998, Tech Serve Solutions arranges compliant international dispatch with the necessary export and transport paperwork.
How do I request a sample or a quote?
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Contact Tech Serve Solutions with the product name or CAS 1186310-83-7, the quantity you need and your delivery destination, and our team will respond with availability, lead time, specification and a formal quotation. Samples can be discussed for evaluation, subject to availability.
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