4-Hydroxyquinoline-3-carboxylic acid ethyl ester
4-Hydroxyquinoline-3-carboxylic acid ethyl ester (CAS 26892-90-0) is a crystalline heterocyclic building block with the molecular formula C12H11NO3 and a molar mass of 217.22 g/mol. It belongs to the 4-hydroxyquinoline-3-carboxylate family, combining a fused quinoline ring with adjacent hydroxyl and ethyl ester groups. This versatile intermediate is used principally in chemical synthesis and pharmaceutical research. Tech Serve Solutions supplies it as a research-grade reagent to laboratories and manufacturers worldwide.
- Synonyms
- 4-Hydroxyquinoline-3-carboxylic acid ethyl esterEthyl 4-hydroxyquinoline-3-carboxylateEthyl 4-hydroxy-3-quinolinecarboxylate4-Hydroxy-3-quinolinecarboxylic acid ethyl esterCAS 26892-90-0
Heterocyclic building block
Serves as a quinoline-based scaffold in multi-step organic synthesis. The reactive hydroxyl, ester and ring nitrogen functionalities provide convenient handles for further derivatisation.
Pharmaceutical intermediate
Used in medicinal chemistry programmes as a precursor to more complex quinoline derivatives. The 4-hydroxyquinoline-3-carboxylate motif is a recognised core in numerous bioactive structures.
Research and discovery chemistry
Applied as a reference compound and starting material in laboratory-scale exploratory synthesis, including the preparation of fused-ring and substituted quinoline libraries.
Ester and ring functionalisation
The ethyl ester can be hydrolysed or transesterified to access the corresponding carboxylic acid and other esters, while the hydroxyl group supports etherification and related transformations.
| Molecular weight | 217.22 |
|---|---|
| Empirical formula | C12H11NO3 |
Hazard statements
- H319Causes serious eye irritation
Precautionary statements
- P305IF IN EYES
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Hydroxyquinoline-3-carboxylic acid ethyl ester used for?
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It is used mainly as a heterocyclic building block and pharmaceutical intermediate in chemical synthesis. Its quinoline core, hydroxyl, ester and ring-nitrogen groups make it a useful precursor for preparing more complex quinoline derivatives in research and discovery chemistry.
What is the CAS number and molecular formula of 4-Hydroxyquinoline-3-carboxylic acid ethyl ester?
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The CAS number is 26892-90-0 and the molecular formula is C12H11NO3 (Hill notation), corresponding to a molecular weight of 217.22 g/mol.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound as a research/technical-grade reagent for laboratory and manufacturing use. We do not represent it as USP, BP or EP pharmacopoeial grade. A current Certificate of Analysis with the actual assay can be provided on request before purchase.
What are the safety and handling precautions?
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It is classified under GHS07 with the signal word Warning and hazard statement H319 (causes serious eye irritation). Wear suitable eye protection and gloves, avoid generating dust, and if it enters the eyes, rinse cautiously with water for several minutes and remove contact lenses if present (P305 + P351 + P338). It carries German Water Hazard Class WGK 3. Always consult the Safety Data Sheet before use.
How is 4-Hydroxyquinoline-3-carboxylic acid ethyl ester packed, shipped and exported?
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It is supplied in laboratory and bulk pack sizes using sealed, appropriately labelled containers. Each consignment ships with the relevant Safety Data Sheet and Certificate of Analysis, and is dispatched to international destinations in line with applicable transport and export regulations.
How do I request a sample or quote?
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Contact Tech Serve Solutions with your required quantity, packaging and destination, and our team will respond with availability, a Certificate of Analysis and a formal quotation. Samples can be arranged for qualification where appropriate.
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