5-Chloro-2-methylene-1,3,3-trimethylindoline
5-Chloro-2-methylene-1,3,3-trimethylindoline (CAS 6872-17-9) is a chlorinated methyleneindoline building block with the molecular formula C12H14ClN and a molar mass of 207.70 g/mol. A Fischer-base-type reactive heterocycle, its exocyclic methylene group makes it a versatile precursor in chemical synthesis, notably for preparing spiropyran photochromic compounds and related indoline-derived dyes. Tech Serve Solutions supplies it as a research-grade reagent (assay 95%) for laboratory and fine-chemical applications worldwide.
- Synonyms
- 5-Chloro-2-methylene-1,3,3-trimethylindoline5-Chloro-1,3,3-trimethyl-2-methyleneindoline5-Chloro-1,3,3-trimethyl-2-methylideneindoline2-Methylene-5-chloro-1,3,3-trimethylindolineCAS 6872-17-9C12H14ClNMFCD00005814
Spiropyran synthesis
Serves as a key indoline precursor in the preparation of spiro[2H-1-benzopyran-2,2'-indoline] derivatives, including chlorinated spiropyrans. These compounds are widely studied for their photochromic behaviour.
Photochromic and functional dye chemistry
The reactive exocyclic methylene group condenses readily with carbonyl and aromatic partners, making the compound a useful intermediate for indoline-based dyes and switchable molecular systems.
Heterocyclic building block
Used as a halogenated heterocyclic building block in chemical synthesis, where the 5-chloro substituent offers a handle for further functionalisation of the indoline scaffold.
Research and method development
Applied in academic and industrial laboratories for exploratory synthesis, structure-activity studies and the development of new indoline and benzopyran derivatives.
| Molecular weight | 207.70 |
|---|---|
| Empirical formula | C12H14ClN |
| Assay | 95% |
| Density | 1.083 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.594(lit.) |
| Application | 5-Chloro-2-methylene-1,3,3-trimethylindoline was used in the synthesis of 5′,6-dichloro-1′,3′,3′-trimethylspiro[2H-1-benzopyran-2,2′-indoline]1. |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-Chloro-2-methylene-1,3,3-trimethylindoline used for?
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It is used mainly as a synthetic building block. Its reactive exocyclic methylene group makes it a precursor to spiropyran photochromic compounds and other indoline-derived dyes and heterocyclic intermediates in fine-chemical and research applications.
What is the CAS number and molecular formula of 5-Chloro-2-methylene-1,3,3-trimethylindoline?
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The CAS number is 6872-17-9 and the molecular formula is C12H14ClN, with a molecular weight of 207.70 g/mol. The MDL number is MFCD00005814 and the EC number is 229-972-6.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this material as a research-grade reagent with a typical assay of 95%. Reported physical data include a refractive index of n20/D 1.594 and a density of 1.083 g/mL at 25 °C. We do not represent it as USP, BP or EP grade; a certificate of analysis is provided with each batch.
What are the safety and handling requirements?
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It is classified under GHS07 with the signal word Warning and hazard statements H315 (causes skin irritation), H319 (causes serious eye irritation) and H335 (may cause respiratory irritation). Handle with gloves, eye protection and adequate ventilation or suitable respiratory protection (P261, P305+P351+P338). It has a flash point of 113 °C and a German Water Hazard Class (WGK) of 3; always consult the Safety Data Sheet before use.
How is 5-Chloro-2-methylene-1,3,3-trimethylindoline packed, shipped and exported?
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The product is packed in appropriate sealed containers to preserve stability, with packaging sizes available to suit laboratory and bulk requirements. Each consignment is documented and labelled to GHS standards, and Tech Serve Solutions arranges compliant export and international shipping with full supporting paperwork.
How do I request a sample or quote?
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Contact Tech Serve Solutions with your required quantity, grade and destination, and our team will respond with availability, lead time and a formal quotation. Samples can be arranged on request, subject to availability and applicable regulations.
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