N-(2-Chloro-6-(hydroxymethyl)pyridin-3-yl)pivalamide
N-(2-Chloro-6-(hydroxymethyl)pyridin-3-yl)pivalamide (CAS 1142191-92-1, C11H15ClN2O2, molar mass 242.70 g/mol) is a multifunctional pyridine building block. It combines a chloro substituent, a primary hydroxymethyl group and a pivaloyl-protected amine on a single heterocyclic core, making it a versatile intermediate for medicinal chemistry and chemical synthesis. Tech Serve Solutions supplies it as a research-grade building block to laboratories and manufacturers worldwide.
- Synonyms
- N-(2-Chloro-6-(hydroxymethyl)pyridin-3-yl)pivalamideN-[2-chloro-6-(hydroxymethyl)pyridin-3-yl]-2,2-dimethylpropanamideN-[2-chloro-6-(hydroxymethyl)-3-pyridinyl]-2,2-dimethylpropanamide2,2-dimethyl-N-[2-chloro-6-(hydroxymethyl)pyridin-3-yl]propanamideCAS 1142191-92-1
Pharmaceutical intermediate
Serves as a building block in the synthesis of pharmaceutical candidates and active pharmaceutical ingredients. Its substituted pyridine scaffold is a common motif in medicinal chemistry programmes.
Heterocyclic building block
Used in chemical synthesis to construct more elaborate pyridine and fused heterocyclic systems. The three differentiated functional groups allow selective, sequential transformation.
Cross-coupling and substitution chemistry
The ring chlorine provides a reactive handle for palladium-catalysed cross-coupling and nucleophilic aromatic substitution, enabling further structural elaboration of the core.
Functional-group manipulation
The primary hydroxymethyl group can be oxidised, halogenated or otherwise derivatised, while the pivalamide acts as a robust protecting group for the ring amine during multi-step routes.
Research and discovery use
Applied in laboratory research and discovery-scale synthesis where a defined, multifunctional pyridine intermediate is required. Supplied for research and manufacturing use, not for direct human or veterinary administration.
| Molecular weight | 242.70 |
|---|---|
| Empirical formula | C11H15ClN2O2 |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N-(2-Chloro-6-(hydroxymethyl)pyridin-3-yl)pivalamide used for?
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It is used as a research-grade pyridine building block and intermediate in chemical and pharmaceutical synthesis. Its chloro, hydroxymethyl and pivalamide groups make it useful for cross-coupling, substitution and selective functional-group chemistry when building more complex heterocyclic molecules.
What is the CAS number and molecular formula of N-(2-Chloro-6-(hydroxymethyl)pyridin-3-yl)pivalamide?
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The CAS number is 1142191-92-1 and the molecular formula is C11H15ClN2O2 (Hill notation), corresponding to a molecular weight of 242.70 g/mol.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound as a research/technical-grade building block. We do not represent it as USP, BP or EP pharmacopoeia grade. A current Certificate of Analysis stating the actual assay and specification for each batch is provided on request, so you can confirm suitability before purchase.
How should N-(2-Chloro-6-(hydroxymethyl)pyridin-3-yl)pivalamide be handled and stored?
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A full GHS hazard classification is not specified in our data, so handle it as a research chemical of unknown hazard. Use appropriate personal protective equipment, work in a fume hood, avoid dust, skin and eye contact, and keep it tightly closed in a cool, dry, well-ventilated store away from incompatible materials. Always consult the current Safety Data Sheet, which we supply with every order, before use.
How is N-(2-Chloro-6-(hydroxymethyl)pyridin-3-yl)pivalamide packed, shipped and exported?
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It is packed in sealed, labelled containers sized from gram quantities to bulk research scale, with packaging selected to protect the material in transit. As a specialist exporter since 1998, Tech Serve Solutions arranges compliant international shipping with full documentation, including the Certificate of Analysis and Safety Data Sheet.
How do I request a sample or quote?
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Contact Tech Serve Solutions with your required quantity, destination and intended packaging, quoting CAS 1142191-92-1. We will respond with availability, lead time, specification and a formal quotation, and can arrange a sample where appropriate.
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