Holmium(III) trifluoromethanesulfonate
Holmium(III) trifluoromethanesulfonate (CAS 139177-63-2), with the molecular formula (CF3SO3)3Ho, is a valuable compound in synthetic chemistry. It functions as a water-tolerant Lewis acid, particularly effective in catalyzing reactions such as the Aldol reaction between silyl enol ethers and aldehydes. This triflate salt offers unique reactivity profiles for various organic transformations.
- IUPAC
- Holmium(III) triflate,Trifluoromethanesulfonic acid holmium(III) salt
- Synonyms
- Holmium(III) triflateTrifluoromethanesulfonic acid holmium(III) salt

Aldol Reaction Catalyst
Holmium(III) trifluoromethanesulfonate serves as a potent Lewis acid catalyst in the Aldol reaction. It facilitates the condensation between silyl enol ethers and aldehydes, enabling the formation of carbon-carbon bonds under specific reaction conditions.
Water-Tolerant Lewis Acid
Its characteristic as a water-tolerant Lewis acid makes it useful in synthetic procedures where moisture may be present or difficult to exclude entirely. This property simplifies experimental setups and expands its applicability in organic synthesis.
Organic Synthesis Reagent
This holmium salt is employed as a reagent in various organic synthesis pathways. Its triflate anion contributes to its Lewis acidity, making it an effective tool for promoting specific chemical transformations.
| Molecular weight | 612.14 |
|---|---|
| Linear formula | (CF3SO3)3Ho |
| Assay | 98% |
| Application | A water-tolerant Lewis acid used in the Aldol reaction of silyl enol ethers with aldehydes.7 |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Holmium(III) trifluoromethanesulfonate used for?
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Holmium(III) trifluoromethanesulfonate is primarily used as a water-tolerant Lewis acid catalyst in organic synthesis, notably for facilitating the Aldol reaction between silyl enol ethers and aldehydes.
What is the CAS number and formula for Holmium(III) trifluoromethanesulfonate?
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The CAS number is 139177-63-2, and its linear formula is (CF3SO3)3Ho.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Holmium(III) trifluoromethanesulfonate with an assay of 98%. We do not represent this product as USP, BP, or EP grade; it is suitable for research and chemical synthesis applications.
How should Holmium(III) trifluoromethanesulfonate be handled safely?
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Handle with appropriate personal protective equipment, including a dust mask (type N95 or equivalent), eyeshields, and gloves. Avoid breathing dust. In case of eye contact, rinse cautiously with water for several minutes and seek medical attention. Ensure good ventilation in the work area.
Is Holmium(III) trifluoromethanesulfonate a controlled substance?
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No, the provided data does not indicate that Holmium(III) trifluoromethanesulfonate is a controlled substance.
How can I request a sample or quote for Holmium(III) trifluoromethanesulfonate?
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To request a sample or a quote, please contact our sales team through the website or by calling our main office. Please specify the quantity required and your shipping destination.
How is Holmium(III) trifluoromethanesulfonate packed and shipped?
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Holmium(III) trifluoromethanesulfonate is carefully packed to ensure safe transport and is available for export globally. Specific packaging details will be confirmed upon order.
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